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Pioglitazone
  • Synonyms: AD-4833, U 72107
  • ATC: A10BG03
  • Use: Lorem  Lorem 
  • Chemical name: Lorem ipsum dolor sit amet, consetetur sadipscing elitr, sed diam
  • Formula: Lorem ipsum dolor sit amet,
  • MW:356.45 g/mol
  • CAS-RN:111025-46-8
  • InChI Key:HYAFETHFCAUJAY-UHFFFAOYSA-N
  • InChI:InChI=1S/C19H20N2O3S/c1-​2-​13-​3-​6-​15(20-​12-​13)​9-​10-​24-​16-​7-​4-​14(5-​8-​16)​11-​17-​18(22)​21-​19(23)​25-​17/h3-​8,​12,​17H,​2,​9-​11H2,​1H3,​(H,​21,​22,​23)

Derivatives

    hydrochloride

  • Formula: C19H20N2O3S • HCl
  • MW:392.91 g/mol
  • CAS-RN:112529-15-4

Substance Classes

Synthesis Path




















Substances Referenced in Synthesis Path

CAS-RN Formula Chemical Name CAS Index Name
96-33-3 C4H6O2 acrylic acid methyl ester 2-Propenoic acid, methyl ester
23616-79-7 C19H34ClN benzyltributylammonium chloride Benzenemethanaminium, N,N,N-tributyl-, chloride
144809-27-8 C16H19NO3S 5-ethyl-2-pyridineethanol 4-methylbenzenesulfonate (ester) 2-Pyridineethanol, 5-ethyl-, 4-methylbenzenesulfonate (ester)
114393-97-4 C16H17NO2 4-[2-(5-ethyl-2-pyridinyl)ethoxy]benzaldehyde Benzaldehyde, 4-[2-(5-ethyl-2-pyridinyl)ethoxy]-
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem

Trade Names

Country Trade Name Vendor Annotation
D Lorem Lorem
Lorem Lorem comb.
F Lorem Lorem
Lorem Lorem
GB Lorem Lorem
I Lorem Lorem
J Lorem Lorem
USA Lorem Lorem
Lorem Lorem Lorem ,1999
Lorem Lorem
(wfm = withdrawn from market)

Formulations

  • Loremipsumdolorsitamet,consetetursadipscingelitr,sed

References

    • a Sohda, T. et al.: Arzneim.-Forsch. (ARZNAD) 40 (1), 37-42 (1990).
    •  US 9 999 999 (Takeda; 18.8.1987; J-prior. 19.1.1985).
    •  EP 999 999 (Takeda; appl. 15.1.1986; J-prior. 19.1.1985).
    • b, c EP 999 999 (Takeda; appl. 16.3.1992; J-prior. 25.3.1991).
    •  Momose, Y. et al.: Chem. Pharm. Bull. (CPBTAL) 39 (6), 1440-1445 (1991).
    • c EP 999 999 (Takeda; appl. 26.6.1997; J-prior. 27.6.1996).
    • d WO 9 999 999 (Upjohn; appl. 4.12.1992; USA-prior. 20.12.1991).

  • synthesis of metabolites:

    • Tanis, S.P. et al.: J. Med. Chem. (JMCMAR) 39 (26), 5053-5063 (1996).
    • WO 9 999 999 (Upjohn; appl. 21.4.1993; USA-prior. 5.5.1992).
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