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Asciminib
  • Synonyms: ABL001
  • ATC: L01EA06
  • Use: Lorem 
  • Chemical name: Lorem ipsum dolor sit amet, consetetur sadipscing elitr, sed diam
  • Formula: Lorem ipsum dolor sit amet,
  • MW:449.8 g/mol
  • CAS-RN:1492952-76-7
  • InChI Key:VOVZXURTCKPRDQ-CQSZACIVSA-N
  • InChI:InChI=1S/C20H18ClF2N5O3/c21-​20(22,​23)​31-​15-​3-​1-​13(2-​4-​15)​26-​19(30)​12-​9-​16(17-​5-​7-​25-​27-​17)​18(24-​10-​12)​28-​8-​6-​14(29)​11-​28/h1-​5,​7,​9-​10,​14,​29H,​6,​8,​11H2,​(H,​25,​27)​(H,​26,​30)/t14-​/m1/s1

Derivatives

    Hydrochloride

  • Formula: C20H19Cl2F2N5O3
  • MW:486.3 g/mol
  • CAS-RN:2119669-71-3

Substance Classes

Synthesis Path

Substances Referenced in Synthesis Path

CAS-RN Formula Chemical Name CAS Index Name
29241-62-1 C6H3BrClNO2 5-bromo-6-chloro-nicotinic acid
39065-95-7 C7H6ClF2NO 4-(chlorodifluoromethoxy) aniline
C13H7BrCl2F2N2O2 5-bromo-6-chloro-N-(4-(chlorodifluoromethoxy)phenyl) nicotinamide
2799-21-5 C4H9NO (R)-pyrrolidin-3-ol
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem

Trade Names

Country Trade Name Vendor Annotation
USA Lorem Lorem
(wfm = withdrawn from market)

Formulations

  • Loremipsumdolorsitamet,consetetur

References

    • a) Schoepfer, J. et al, J. Med. Chem., (2018) 61, 8120-8135.
    • US 9 999 999 (Novartis; 9.9.2014; appl. 7.3.2012; USA-prior. 2.12.2005).
    • WO 9999 999999 (Novartis; 21.11.2013; appl. 9.5.2013; USA-prior. 15.5.2012).
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