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Abrocitinib

  • Synonyms: PF-04965842
  • ATC: D11AH08
  • Use: Lorem 
  • Chemical name: Lorem ipsum dolor sit amet, consetetur sadipscing elitr, sed diam
  • Formula: Lorem ipsum dolor sit amet,
  • MW:323.41 g/mol
  • CAS-RN:1622902-68-4
  • InChI Key:IUEWXNHSKRWHDY-PHIMTYICSA-N
  • InChI:InChI=1S/C14H21N5O2S/c1-​3-​6-​22(20,​21)​18-​10-​7-​11(8-​10)​19(2)​14-​12-​4-​5-​15-​13(12)​16-​9-​17-​14/h4-​5,​9-​11,​18H,​3,​6-​8H2,​1-​2H3,​(H,​15,​16,​17)/t10-,​11+

Substance Classes

Synthesis Path







Substances Referenced in Synthesis Path

CAS-RN Formula Chemical Name CAS Index Name
23761-23-1 C5H6O3 3-oxocyclobutane-1-carboxylic acid -
130369-36-7 C12H13NO3 benzyl 3-oxocyclobutyl-carbamate -
2204290-99-1 C13H19ClN2O2 benzyl [cis(methylamino)-cyclobutyl]carbamate hydrochloride -
- C13H10ClN3O2S N-tosyl-6-chloro-7-deazapurine -
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem

Trade Names

Country Trade Name Vendor Annotation
J Lorem Lorem
GB Lorem Lorem
EU Lorem Lorem
USA Lorem Lorem
(wfm = withdrawn from market)

Formulations

  • Loremipsumdolorsitamet,consetetursadipscing

References

    • Bieber, T. et al., N. Engl. J. Med., (2021) 384, 1101-1112.
    • a) Vazquez, M.L. et al., J. Med. Chem., (2018) 61(3), 1130-1152.
    • US 9 999 999 (Pfizer; 19.5.2015; appl. 19.2.2014; USA-prior. 22.2.2013).
    • US 9 999 999 (Pfizer; 24.1.2017; appl. 18.5.2015; USA-prior. 22.2.2013).
    • b) Connor, C.G. et al., Org. Process Res. Dev., (2021) 25, 608-615.
    • WO 9999 999999 (Pfizer; 9.1.2020; appl. 3.7.2019; USA-prior. 6.7.2018).
    • US 99 999 999 (Pfizer; 22.2.2022; appl. 29.9.2020; USA-prior. 6.7.2018).
    • Kocienski, P., Synfacts, (2021) 17(6), 0606.
    • a+b) Zhan, D.G. et al., Drugs of the Future, (2021) 46(6), 431-441.
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