Please log in to see the full text of this API!
Betamethasone
-
ATC:
A07EA04; C05AA05; D07AC01; D07XC01; H02AB01; R01AD06; R03BA04; S01BA06; S01CB04; S03CA06
-
Use:
Lorem
-
Chemical name:
Lorem ipsum dolor sit amet, consetetur sadipscing elitr, sed diam
-
Formula:
Lorem ipsum dolor sit amet,
-
MW:392.47 g/mol
-
CAS-RN:378-44-9
-
InChI Key:UREBDLICKHMUKA-DVTGEIKXSA-N
-
InChI:InChI=1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15-,16-,17-,19-,20-,21-,22-/m0/s1
-
EINECS:206-825-4
-
LD50:>4.5 g/kg (M, p.o.)
Substances Referenced in Synthesis Path
| CAS-RN |
Formula |
Chemical Name |
CAS Index Name |
| 108-24-7 |
C4H6O3 |
acetic anhydride |
Acetic acid, anhydride |
|
C24H34Br2O6 |
21-acetoxy-2,4-dibromo-11α,17α-dihydroxy-16β-methyl-5β-pregnane-3,20-dione |
|
| 5078-99-9 |
C24H32O6 |
21-acetoxy-11α,17α-dihydroxy-16β-methylpregna-1,4-diene-3,20-dione |
Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-11,17-dihydroxy-16-methyl-, (11α,16β)- |
| 5078-98-8 |
C24H36O6 |
21-acetoxy-11α,17α-dihydroxy-16β-methyl-5β-pregnane-3,20-dione |
5β-Pregnane-3,20-dione, 11α,17,21-trihydroxy-16β-methyl-, 21-acetate |
| Lorem |
Lorem |
Lorem |
Lorem |
| Lorem |
Lorem |
Lorem |
Lorem |
| Lorem |
Lorem |
Lorem |
Lorem |
| Lorem |
Lorem |
Lorem |
Lorem |
| Lorem |
Lorem |
Lorem |
Lorem |
| Lorem |
Lorem |
Lorem |
Lorem |
| Lorem |
Lorem |
Lorem |
Lorem |
| Lorem |
Lorem |
Lorem |
Lorem |
| Lorem |
Lorem |
Lorem |
Lorem |
| Lorem |
Lorem |
Lorem |
Lorem |
| Lorem |
Lorem |
Lorem |
Lorem |
| Lorem |
Lorem |
Lorem |
Lorem |
| Lorem |
Lorem |
Lorem |
Lorem |
| Lorem |
Lorem |
Lorem |
Lorem |
| Lorem |
Lorem |
Lorem |
Lorem |
| Lorem |
Lorem |
Lorem |
Lorem |
| Lorem |
Lorem |
Lorem |
Lorem |
| Lorem |
Lorem |
Lorem |
Lorem |
| Lorem |
Lorem |
Lorem |
Lorem |
| Lorem |
Lorem |
Lorem |
Lorem |
| Lorem |
Lorem |
Lorem |
Lorem |
| Lorem |
Lorem |
Lorem |
Lorem |
| Lorem |
Lorem |
Lorem |
Lorem |
| Lorem |
Lorem |
Lorem |
Lorem |
| Lorem |
Lorem |
Lorem |
Lorem |
| Lorem |
Lorem |
Lorem |
Lorem |
| Lorem |
Lorem |
Lorem |
Lorem |
| Lorem |
Lorem |
Lorem |
Lorem |
| Lorem |
Lorem |
Lorem |
Lorem |
| Lorem |
Lorem |
Lorem |
Lorem |
| Lorem |
Lorem |
Lorem |
Lorem |
| Lorem |
Lorem |
Lorem |
Lorem |
| Lorem |
Lorem |
Lorem |
Lorem |
| Lorem |
Lorem |
Lorem |
Lorem |
| Lorem |
Lorem |
Lorem |
Lorem |
| Lorem |
Lorem |
Lorem |
Lorem |
| Lorem |
Lorem |
Lorem |
Lorem |
Trade Names
| Country |
Trade Name |
Vendor |
Annotation |
| D |
Lorem |
Lorem
|
|
| F |
Lorem |
Lorem
|
|
| Lorem |
Lorem
|
|
| Lorem |
Lorem
|
|
| Lorem |
Lorem
|
|
| Lorem |
Lorem
|
|
| Lorem |
Lorem
|
|
| Lorem |
Lorem
|
|
| Lorem |
Lorem
|
|
| Lorem ipsum |
|
|
| GB |
Lorem |
Lorem
|
|
| Lorem |
Lorem
|
|
| Lorem |
Lorem
|
|
| Lorem |
Lorem
|
|
| Lorem |
Lorem
|
comb. |
| Lorem |
Lorem
|
comb. |
| I |
Lorem |
Lorem
|
as benzoate |
| Lorem |
Lorem
|
as phosphate |
| Lorem |
Lorem
|
as valeroacetate |
| Lorem |
Lorem
|
comb. |
| Lorem |
Lorem
|
|
| Lorem |
Lorem
|
comb. |
| Lorem |
Lorem
|
as valerate |
| Lorem |
Lorem
|
|
| Lorem |
Lorem
|
as dipropionate |
| Lorem |
Lorem
|
as valerate |
| J |
Lorem |
Lorem
|
comb. with d-chlorpheniramine |
| Lorem |
Lorem
|
|
| USA |
Lorem |
Lorem
|
|
(wfm = withdrawn from market)
Formulations
- Loremipsumdolorsitamet,consetetursadipscingelitr,seddiamnonumyeirmodtemporinviduntutlaboreetdoloremagna
References
-
- a US 9 999 999 (Schering Corp.; 5.1.1965; prior. 23.7.1957, 8.5.1958).
- b Oliveto, E.P. et al.: J. Am. Chem. Soc. (JACSAT) 80, 9999 (1958).
- Oliveto, E.P. et al.: J. Am. Chem. Soc. (JACSAT) 80, 9999 (1958).
- c US 9 999 999 (Roussel-Uclaf; 17.9.1963; appl. 26.7.1962; F-prior. 18.8.1961).
- Julian, P.L. et al.: J. Am. Chem. Soc. (JACSAT) 77, 9999 (1955).
-
alternative syntheses:
- US 9 999 999 (Merck & Co.; 11.9.1962; prior. 19.3.1958, 1.3.1960).
- Taub, D. et al.: J. Am. Chem. Soc. (JACSAT) 80, 9999 (1958); 28, 9999 (1960).
- US 9 999 999 (Upjohn; 9.8.1977; appl. 17.1.1975).
-
technology for the reaction of epoxide X with H2F2:
- McGhie,S. et al.: Org. Process Res. Dev. (OPRDFK) 6, 898-900 (2002).
