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Capmatinib
  • Synonyms: INC280
  • ATC: L01EX17
  • Use: Lorem 
  • Chemical name: Lorem ipsum dolor sit amet, consetetur sadipscing elitr, sed diam
  • Formula: Lorem ipsum dolor sit amet,
  • MW:412.43 g/mol
  • CAS-RN:1029712-80-8
  • InChI Key:LIOLIMKSCNQPLV-UHFFFAOYSA-N
  • InChI:InChI=1S/C23H17FN6O/c1-​25-​22(31)​18-​6-​5-​16(11-​19(18)​24)​21-​13-​28-​23-​27-​12-​17(30(23)​29-​21)​10-​14-​4-​7-​20-​15(9-​14)​3-​2-​8-​26-​20/h2-​9,​11-​13H,​10H2,​1H3,​(H,​25,​31)

Derivatives

    Dihydrochloride

  • Formula: C23H21Cl2FN6O2
  • MW:503.36 g/mol
  • CAS-RN:1865733-40-9

Substance Classes

Synthesis Path






Substances Referenced in Synthesis Path

CAS-RN Formula Chemical Name CAS Index Name
153556-42-4 C7H4BrFO2 4-bromo-3-fluoro-benzoic acid
1117-97-1 C2H7NO N,O-dimethylhydroxylamine
343564-56-7 C9H9BrFNO2 4-bromo-3-fluoro-N-methoxy-N-methylbenzamide
C12H14BrFO3 1-(4-bromo-3-fluorophenyl-2,2-diethoxyethanone
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Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem

Trade Names

Country Trade Name Vendor Annotation
USA Lorem Lorem
(wfm = withdrawn from market)

Formulations

  • Loremipsumdolorsitamet,consetetursadipscingelitr,

References

    • Lin, X. et al, Chin. Cancer Res., (2011), 17(22), 7127-7138.
    • a) US 9 999 999 (Incyte Corp.; 3.8.2010; appl. 19.11.2007; USA-prior. 22.11.2006).
    • b) US 9999 9999999 (Incyte Corp.; 6.6.2019; appl. 7.2.2019; USA-prior. 21.5.2008).

  • Tablet formulation:

    • US 9999 999999 (Novartis AG; 17.1.2019; appl. 18.9.2018; USA-prior. 25.7.2014).

  • Combination products with Tyrosine Kinase Inhibitors:

    • US 9999 999999 (Novartis AG; 12.4.2018; appl. 13.12.2017; USA-prior. 3.4.2012).
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