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Capmatinib

  • Synonyms: INC280
  • ATC: L01EX17
  • Use: Lorem 
  • Chemical name: Lorem ipsum dolor sit amet, consetetur sadipscing elitr, sed diam
  • Formula: Lorem ipsum dolor sit amet,
  • MW:412.43 g/mol
  • CAS-RN:1029712-80-8
  • InChI Key:LIOLIMKSCNQPLV-UHFFFAOYSA-N
  • InChI:InChI=1S/C23H17FN6O/c1-25-22(31)18-6-5-16(11-19(18)24)21-13-28-23-27-12-17(30(23)29-21)10-14-4-7-20-15(9-14)3-2-8-26-20/h2-9,11-13H,10H2,1H3,(H,25,31)

Derivatives

    Dihydrochloride

  • Formula: C23H21Cl2FN6O2
  • MW:503.36 g/mol
  • CAS-RN:1865733-40-9

Substance Classes

Synthesis Path










Substances Referenced in Synthesis Path

CAS-RN Formula Chemical Name CAS Index Name
153556-42-4 C7H4BrFO2 4-bromo-3-fluoro-benzoic acid
1117-97-1 C2H7NO N,O-dimethylhydroxylamine
343564-56-7 C9H9BrFNO2 4-bromo-3-fluoro-N-methoxy-N-methylbenzamide
C12H14BrFO3 1-(4-bromo-3-fluorophenyl-2,2-diethoxyethanone
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Trade Names

Country Trade Name Vendor Annotation
USA Lorem Lorem
(wfm = withdrawn from market)

Formulations

  • Loremipsumdolorsitamet,consetetursadipscingelitr,

References

    • Lin, X. et al, Chin. Cancer Res., (2011), 17(22), 7127-7138.
    • a) US 9 999 999 (Incyte Corp.; 3.8.2010; appl. 19.11.2007; USA-prior. 22.11.2006).
    • b) US 9999 9999999 (Incyte Corp.; 6.6.2019; appl. 7.2.2019; USA-prior. 21.5.2008).
  • Tablet formulation:

    • US 9999 999999 (Novartis AG; 17.1.2019; appl. 18.9.2018; USA-prior. 25.7.2014).
  • Combination products with Tyrosine Kinase Inhibitors:

    • US 9999 999999 (Novartis AG; 12.4.2018; appl. 13.12.2017; USA-prior. 3.4.2012).