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Dexmedetomidine
  • Synonyms: MPV-1440, (S)-Medetomidine
  • ATC: N01A
  • Use: Lorem  Lorem 
  • Chemical name: Lorem ipsum dolor sit amet, consetetur sadipscing elitr, sed diam
  • Formula: Lorem ipsum dolor sit amet,
  • MW:200.29 g/mol
  • CAS-RN:113775-47-6
  • InChI Key:CUHVIMMYOGQXCV-NSHDSACASA-N
  • InChI:InChI=1S/C13H16N2/c1-​9-​5-​4-​6-​12(10(9)​2)​11(3)​13-​7-​14-​8-​15-​13/h4-​8,​11H,​1-​3H3,​(H,​14,​15)/t11-​/m0/s1

Derivatives

    hydrochloride

  • Use:
  • Formula: Lorem ipsum dolor sit amet,
  • MW:236.75 g/mol
  • CAS-RN:145108-58-3

    racemate (medetomidine)

  • Use:
  • Formula: Lorem ipsum dolor sit amet,
  • MW:200.29 g/mol
  • CAS-RN:86347-14-0

Substance Classes

Synthesis Path






Substances Referenced in Synthesis Path

CAS-RN Formula Chemical Name CAS Index Name
18162-48-6 C6H15ClSi tert-butyldimethylsilyl chloride Silane, chloro(1,1-dimethylethyl)dimethyl-
21900-46-9 C9H9ClO 2,3-dimethylbenzoyl chloride
91874-85-0 C12H12N2O 4-(2,3-dimethylbenzoyl)imidazole
129378-52-5 C11H23N3O2SSi 2-[(1,1-dimethylethyl)dimethylsilyl]-N,N-dimethyl-1H-imidazole-1-sulfonamide
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem

Trade Names

Country Trade Name Vendor Annotation
USA Lorem Lorem ,2000
EU Lorem Lorem
Lorem Lorem
(wfm = withdrawn from market)

Formulations

  • Loremipsumdolorsitamet,

References

    • EP 99 999 (Farmos; 2.7.1982; GB-prior. 10.7.1981).
    • GB 9 999 999 (Farmos; 18.1.1989; GB-prior. 16.7.1987).

  • benzyl- and 4-benzoylimidazole derivatives:

    • US 9 999 999 (Farmos; 17.4.1984; USA-prior. 8.7.1979).

  • alternative preparation of medetomidine via low temperature process:

    • Kudzma, L. V.; Turnbull, S. P. jr.: Synthesis (SYNTBF) 1991, 11, 1021.

  • 1-(N,N-dimethylsulfamoyl)imidazole:

    • Chadwick, D. J.; Ngodundo, R. I.: J. Chem. Soc., Perkin Trans. 9 (JCPRB4) 1984, 481.
    • Kim, J. W. et al.: J. Heterocycl. Chem. (JHTCAD) 32, 2, 999 (1995).

  • use of medetomidine as analgesic:

    • EP 999 999 (Orion; 24.4.1991; FI-prior. 17.10.1989).

  • medetomidine:

    • The Merck Index, 13th Ed., 5811, p. 1034.
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