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Dextromethorphan

  • Synonyms: d-Methorphan
  • ATC: R05DA09
  • Use: Lorem  Lorem 
  • Chemical name: Lorem ipsum dolor sit amet, consetetur sadipscing elitr, sed diam
  • Formula: Lorem ipsum dolor sit amet,
  • MW:271.40 g/mol
  • CAS-RN:125-71-3
  • InChI Key:MKXZASYAUGDDCJ-NJAFHUGGSA-N
  • InChI:InChI=1S/C18H25NO/c1-19-10-9-18-8-4-3-5-15(18)17(19)11-13-6-7-14(20-2)12-16(13)18/h6-7,12,15,17H,3-5,8-11H2,1-2H3/t15-,17+,18+/m1/s1
  • EINECS:204-752-2
  • LD50: 210 mg/kg (M, p.o.);
    16.286 mg/kg (R, i.v.); 116 mg/kg (R, p.o.)

Derivatives

    hydrobromide

  • Formula: C18H25NO • HBr
  • MW:352.32 g/mol
  • CAS-RN:125-69-9
  • EINECS:204-750-1
  • LD50: 34 mg/kg (M, i.v.); 165 mg/kg (M, p.o.);
    350 mg/kg (R, p.o.)

    hydrobromide monohydrate

  • Formula: C18H25NO • HBr • H2O
  • MW:370.33 g/mol
  • CAS-RN:6700-34-1

Substance Classes

Synthesis Path






Substances Referenced in Synthesis Path

CAS-RN Formula Chemical Name CAS Index Name
297-90-5 C17H23NO (±)-3-hydroxy-N-methylmorphinan Morphinan-3-ol, 17-methyl-
67-56-1 CH4O methanol Methanol
510-53-2 C18H25NO (±)-3-methoxy-N-methylmorphinan Morphinan, 3-methoxy-17-methyl-

Trade Names

Country Trade Name Vendor Annotation
D Lorem Lorem
Lorem ipsum Lorem
Lorem ipsum Lorem
Lorem ipsum Lorem
Lorem ipsum dolor Lorem
F Lorem Lorem
Lorem Lorem
Lorem Lorem
Lorem Lorem
Lorem Lorem
Lorem Lorem
Lorem ipsum Lorem
I Lorem Lorem
Lorem Lorem
Lorem Lorem
Lorem
Lorem Lorem
J Lorem Lorem
USA Lorem ipsum Lorem
Lorem ipsum dolor Lorem
Lorem ipsum Lorem
Lorem ipsum Lorem
(wfm = withdrawn from market)

Formulations

  • Loremipsumdolorsitamet,consetetursadipscingelitr,seddiamnonumyeirmodtemporinviduntutlaboreetdoloremagnaaliquyamerat,seddiamvoluptua.

References

    • Schnider, O.; Grüssner, A.: Helv. Chim. Acta (HCACAV) 34, 2211 (1951).
    • US 9 999 999 (Roche; 1954; CH-prior. 1949).
  • medical use as analgesic:

    • US 9 999 999 (Nelson Research; 23.2.1982; appl. 15.4.1980).
    • US 9 999 999 (Nelson Research; 1.5.1984; prior. 10.12.1981, 29.3.1982).
  • nasal use as antitussive:

    • US 9 999 999 (Roche; 12.6.1984; appl. 7.9.1982).