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Daridorexant
  • Synonyms: Nemorexant; ACT-541468; Daridorexant hydrochloride
  • ATC: not yet assigned (NO5C)
  • Use: Lorem 
  • Chemical name: Lorem ipsum dolor sit amet, consetetur sadipscing elitr, sed diam
  • Formula: Lorem ipsum dolor sit amet,
  • MW:450.93 g/mol
  • CAS-RN:1505484-82-1
  • InChI Key:NBGABHGMJVIVBW-QHCPKHFHSA-N
  • InChI:InChI=1S/C23H23ClN6O2/c1-​14-​17(24)​6-​7-​18-​20(14)​28-​22(27-​18)​23(2)​9-​4-​12-​29(23)​21(31)​16-​13-​15(32-​3)​5-​8-​19(16)​30-​25-​10-​11-​26-​30/h5-​8,​10-​11,​13H,​4,​9,​12H2,​1-​3H3,​(H,​27,​28)/t23-​/m0/s1

Derivatives

    Hydrochloride

  • Formula: C23H23ClN6O2 • HCl
  • MW:487.38 g/mol
  • CAS-RN:1792993-84-0

Substance Classes

Synthesis Path



Substances Referenced in Synthesis Path

CAS-RN Formula Chemical Name CAS Index Name
42856-71-3 C6H11NO2 (S)-2-methyl-proline (S)-2-methylpyrrolidine-2-carboxylic acid
673487-36-0 C7H9ClN2 6-chloro-2,3-diaminotoluene 4-chloro-3-methylbenzene-1,2-diamine
54413-93-3 C8H7IO3 2-iodo-5-methoxy benzoic acid
288-36-8 C2H3N3 1H-1,2,3-triazole
Lorem Lorem Lorem Lorem

Trade Names

Country Trade Name Vendor Annotation
USA Lorem Lorem
EU Lorem Lorem
(wfm = withdrawn from market)

Formulations

  • Loremipsumdolorsitamet,consetetursadipscingelitr,seddiamnonumyeirmodtemporinviduntutlaboreetdolore

References

    • WO 99999999 (Actelion; 12.12.2013; prior. 04.06.2012).
    • US 9 999 999 (Idorsia; 15.08.2017; prior. 04.06.2012).
    • WO 99999999 (Actelion; 11.06.2015; prior. 04.12.2013).
    • Boss C., Chimia, (2020) 74, 549-560.

  • Synthesis and Crystalline Salt Forms:

    • WO 99999999 (Actelion; 11.06.2015; prior. 03.12.2013).
    • US 9 999 999 (Idorsia; 17.10.2017; prior. 03.12.2013).
    • WO 99999999 (Actelion; 11.06.2015; prior. 03.12.2013).
    • US 99 999 999 (Idorsia; 17.07.2018; prior. 03.12.2013).
    • WO 99999999 (Idorsia; 08.11.2018; prior. 03.05.2017).

  • Medical Use:

    • WO 99999999 (Idorsia; 28.10.2021; prior. 19.04.2020).
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