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Fluazacort

  • Synonyms: Azacortid
  • ATC: D07AB
  • Use: Lorem  Lorem 
  • Chemical name: Lorem ipsum dolor sit amet, consetetur sadipscing elitr, sed diam
  • Formula: Lorem ipsum dolor sit amet,
  • MW:459.51 g/mol
  • CAS-RN:19888-56-3
  • InChI Key:BYZCJOHDXLROEC-RBWIMXSLSA-N
  • InChI:InChI=1S/C25H30FNO6/c1-13-27-25(20(31)12-32-14(2)28)21(33-13)10-18-17-6-5-15-9-16(29)7-8-22(15,3)24(17,26)19(30)11-23(18,25)4/h7-9,17-19,21,30H,5-6,10-12H2,1-4H3/t17-,18-,19-,21+,22-,23-,24-,25+/m0/s1
  • EINECS:243-400-2
  • LD50: 54 mg/kg (M, s.c.);
    580 mg/kg (R, s.c.)

Substance Classes

Synthesis Path



















Substances Referenced in Synthesis Path

CAS-RN Formula Chemical Name CAS Index Name
108-24-7 C4H6O3 acetic anhydride Acetic acid, anhydride
2724-68-7 C23H32O4 3β-acetoxy-11,20-dioxo-16-pregnene Pregn-16-ene-11,20-dione, 3-(acetyloxy)-, (3β,5α)-
19890-70-1 C25H35NO5 (3β,5α,5'β)-21-acetoxy-3-hydroxy-2'-methyl-5H-pregn-9(11)-eno[17,16-d]oxazol-20-one 5'βH-5α-Pregn-9(11)-eno[17,16-d]oxazol-20-one, 3β,21-dihydroxy-2'-methyl-, 21-acetate
5070-96-2 C25H35NO5 (3β,5α,5'β)-3-acetoxy-2'-methyl-5'H-pregnano[17,16-d]oxazole-11,20-dione 5'H-Pregnano[17,16-d]oxazole-11,20-dione, 3-(acetyloxy)-2'-methyl-, (3β,5α,16β)-
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem

Trade Names

Country Trade Name Vendor Annotation
I Lorem ipsum Lorem wfm
(wfm = withdrawn from market)

Formulations

  • Loremipsumdolor

References

    • a DOS 9 999 999 (Lepetit; appl. 7.1.1967; GB-prior. 11.1.1966, 11.7.1966, 29.9.1966).
    •  US 9 999 999 (Lepetit; 12.8.1969; appl. 1967; GB-prior. 1.11.1966).
  • synthesis of starting compound:

    • Nathansohn, G. et al.: J. Med. Chem. (JMCMAR) 10, 799 (1967).
    • Nathansohn, G. et al.: Gazz. Chim. Ital. (GCITA9) 95, 1338 (1965).
    • DE 9 999 999 (Gruppo Lepetit; appl. 23.12.1966; GB-prior. 11.1.1966, 11.7.1966, 29.9.1966).
    • US 9 999 999 (Gruppo Lepetit; 30.11.1971; GB-prior. 11.1.1966).
  • review:

    • Nathanson, G. et al.: Steroids (STEDAM) 13, 365 (1969).
  • alternative synthesis of VI:

    • b Nathansohn, G. et al.: J. Med. Chem. (JMCMAR) 10, 799 (1967).
    •  Nathansohn, G. et al.: Steroids (STEDAM) 13, 383 (1969).
    • DOS 9 999 999 (Lepetit; appl. 23.12.1966; GB-prior. 11.1.1966, 11.7.1966, 29.9.1966).
    • DOS 9 999 999 (Lepetit; appl. 23.12.1966; GB-prior. 11.1.1966, 11.7.1966, 29.9.1966).