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Flunisolide
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ATC:
R01AD04; R03BA03
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Use:
Lorem
Lorem
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Chemical name:
Lorem ipsum dolor sit amet, consetetur sadipscing elitr, sed diam
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Formula:
Lorem ipsum dolor sit amet,
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MW:434.50 g/mol
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CAS-RN:3385-03-3
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InChI Key:XSFJVAJPIHIPKU-XWCQMRHXSA-N
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InChI:InChI=1S/C24H31FO6/c1-21(2)30-19-9-14-13-8-16(25)15-7-12(27)5-6-22(15,3)20(13)17(28)10-23(14,4)24(19,31-21)18(29)11-26/h5-7,13-14,16-17,19-20,26,28H,8-11H2,1-4H3/t13-,14-,16-,17-,19+,20+,22-,23-,24+/m0/s1
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EINECS:222-193-2
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LD50: >76 μg/kg (M, i.v.); >500 μg/kg (M, p.o.);
>51 mg/kg (R, i.v.); >500 μg/kg (R, p.o.)
Derivatives
hydrate (2:1)
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Formula:
C24H31FO6 • 1/2H2O
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MW:887.02 g/mol
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CAS-RN:77326-96-6
Substances Referenced in Synthesis Path
| CAS-RN |
Formula |
Chemical Name |
CAS Index Name |
| 67-64-1 |
C3H6O |
acetone |
2-Propanone |
| 25437-07-4 |
C26H33FO6 |
21-acetoxy-3,20-dioxo-6α-fluoro-16α,17α-isopropylidenedioxy-1,4-pregnadiene |
Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-6-fluoro-16,17-[(1-methylethylidene)bis(oxy)]-, (6α,16α)- |
| 1524-88-5 |
C24H33FO6 |
fludroxycortide |
Pregn-4-ene-3,20-dione, 6-fluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]-, (6α,11β,16α)- |
| 53-34-9 |
C21H27FO5 |
6α-fluoroprednisolone |
Pregna-1,4-diene-3,20-dione, 6-fluoro-11,17,21-trihydroxy-, (6α,11β)- |
| Lorem |
Lorem |
Lorem |
Lorem |
Trade Names
| Country |
Trade Name |
Vendor |
Annotation |
| D |
Lorem |
Lorem
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| F |
Lorem |
Lorem
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| GB |
Lorem |
Lorem
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| I |
Lorem |
Lorem
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| Lorem |
Lorem
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| Lorem |
Lorem
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| Lorem |
Lorem
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| Lorem |
Lorem
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| Lorem |
Lorem
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| Lorem |
Lorem
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| Lorem |
Lorem
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| Lorem |
Lorem
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| Lorem |
Lorem
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| Lorem |
Lorem
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| Lorem |
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| USA |
Lorem |
Lorem
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(wfm = withdrawn from market)
Formulations
- Loremipsumdolorsitamet,consetetursadipscingelitr,seddiamnonumyeirmodtemporinvidunt
References
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- a US 9 999 999 (Syntex; 10.3.1964; Mex-prior. 26.1.1960).
- b US 9 999 999 (Syntex; 24.3.1964; Mex-prior. 13.6.1958).
- c GB 999 999 (American Cyanamid; appl. 5.12.1959; USA-prior. 8.12.1958).
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polymorphic form stable in aerosols:
- US 9 999 999 (Syntex; 12.6.1990; appl. 14.9.1981; USA-prior. 27.5.1975, 28.10.1976, 19.11.1976, 4.8.1978, 21.5.1979).
