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Fluticasone propionate

  • ATC: D07AC17; R01AD08; R03BA05
  • Use: Lorem 
  • Chemical name: Lorem ipsum dolor sit amet, consetetur sadipscing elitr, sed diam
  • Formula: Lorem ipsum dolor sit amet,
  • MW:500.58 g/mol
  • CAS-RN:80474-14-2
  • InChI Key:WMWTYOKRWGGJOA-CENSZEJFSA-N
  • InChI:InChI=1S/C25H31F3O5S/c1-5-20(31)33-25(21(32)34-12-26)13(2)8-15-16-10-18(27)17-9-14(29)6-7-22(17,3)24(16,28)19(30)11-23(15,25)4/h6-7,9,13,15-16,18-19,30H,5,8,10-12H2,1-4H3/t13-,15+,16+,18+,19+,22+,23+,24+,25+/m1/s1
  • LD50: >2 g/kg (R, p. o.); >1 g/kg (R, s. c.)

Substance Classes

Synthesis Path








Substances Referenced in Synthesis Path

CAS-RN Formula Chemical Name CAS Index Name
74-97-5 CH2BrCl bromochloromethane Methane, bromochloro-
28416-82-2 C21H26F2O5 (6α,11β,16α,17α)-6,9-difluoro-11,17-dihydroxy-16-methyl-3-oxoandrosta-1,4-diene-17-carboxylic acid Androsta-1,4-diene-17-carboxylic acid, 6,9-difluoro-11,17-dihydroxy-16-methyl-3-oxo-, (6α,11β,16α,17α)-
80474-45-9 C24H30F2O5S (6α,11β,16α,17α)-6,9-difluoro-11-hydroxy-16-methyl-3-oxo-17-(1-oxopropoxy)androsta-1,4-diene-17-carbothioic acid Androsta-1,4-diene-17-carbothioic acid, 6,9-difluoro-11-hydroxy-16-methyl-3-oxo-17-(1-oxopropoxy)-, (6α,11β,16α,17α)-
65429-42-7 C24H30F2O6 (6α,11β,16α,17α)-6,9-difluoro-11-hydroxy-16-methyl-3-oxo-17-(1-oxopropoxy)androsta-1,4-diene-17-carboxylic acid Androsta-1,4-diene-17-carboxylic acid, 6,9-difluoro-11-hydroxy-16-methyl-3-oxo-17-(1-oxopropoxy)-, (6α,11β,16α,17α)-
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem

Trade Names

Country Trade Name Vendor Annotation
D Lorem Lorem
Lorem Lorem
Lorem Lorem
Lorem Lorem
Lorem Lorem
Lorem Lorem comb. with salmeterol
F Lorem Lorem
Lorem Lorem
Lorem Lorem comb.
GB Lorem Lorem
Lorem Lorem
Lorem Lorem
I Lorem ipsum Lorem Lorem comb.
Lorem Lorem
Lorem Lorem
Lorem Lorem
Lorem Lorem
Lorem ipsum Lorem comb.
J Lorem Lorem
Lorem Lorem
Lorem Lorem
USA Lorem Lorem
Lorem Lorem
Lorem Lorem
Lorem Lorem
(wfm = withdrawn from market)

Formulations

  • Loremipsumdolorsitamet,consetetursadipscingelitr,seddiamnonumyeirmodtemporinviduntutlaboreetdoloremagnaaliquyamerat,seddiamvoluptua.Atveroeos

References

    • Phillipps, G.H. et al.: J. Med. Chem. (JMCMAR) 37, 3717 (1994).
    • DE 9 999 999 (Glaxo; appl. 13.2.1981; GB-prior. 15.2.1980).
    • US 9 999 999 (Glaxo; 15.6.1982; appl. 13.2.1981; GB-prior. 15.2.1980).
    • BE 999 999 (Glaxo Group; appl. 13.2.1981; GB-prior. 15.2.1980).
    • IL 999 999 (Chemagis LTD.; IL-prior. 15.5.1994).
  • 17-carboxylic acid by periodic acid oxidation:

    • US 9 999 999 (Glaxo; 6.6.1987; appl. 6.1.1977; GB-prior. 30.8.1974).
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