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Fosinopril
  • Synonyms: Fosenopril, SQ-28555
  • ATC: C09AA09
  • Use: Lorem  Lorem 
  • Chemical name: Lorem ipsum dolor sit amet, consetetur sadipscing elitr, sed diam
  • Formula: Lorem ipsum dolor sit amet,
  • MW:563.67 g/mol
  • CAS-RN:98048-97-6
  • InChI Key:BIDNLKIUORFRQP-XYGFDPSESA-N
  • InChI:InChI=1S/C30H46NO7P/c1-​4-​28(33)​37-​30(22(2)​3)​38-​39(36,​18-​12-​11-​15-​23-​13-​7-​5-​8-​14-​23)​21-​27(32)​31-​20-​25(19-​26(31)​29(34)​35)​24-​16-​9-​6-​10-​17-​24/h5,​7-​8,​13-​14,​22,​24-​26,​30H,​4,​6,​9-​12,​15-​21H2,​1-​3H3,​(H,​34,​35)/t25-,​26+,​30+,​39-​/m1/s1

Derivatives

    sodium salt

  • Formula: C30H45NNaO7P
  • MW:585.65 g/mol
  • CAS-RN:88889-14-9

Substance Classes

Synthesis Path



















Substances Referenced in Synthesis Path

CAS-RN Formula Chemical Name CAS Index Name
100-39-0 C7H7Br benzyl bromide Benzene, (bromomethyl)-
5437-45-6 C9H9BrO2 benzyl bromoacetate Acetic acid, bromo-, phenylmethyl ester
501-53-1 C8H7ClO2 benzyl chloroformate Carbonochloridic acid, phenylmethyl ester
82087-66-9 C19H17NO4 N-benzyloxycarbonyl-3,4-didehydro-4-phenyl-l-proline 1H-Pyrrole-1,2-dicarboxylic acid, 2,5-dihydro-4-phenyl-, 1-(phenylmethyl) ester, (S)-
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem

Trade Names

Country Trade Name Vendor Annotation
D Lorem Lorem Lorem
Lorem Lorem
F Lorem Lorem
Lorem Lorem
GB Lorem Lorem
I Lorem Lorem
Lorem Lorem
Lorem Lorem comb.
(wfm = withdrawn from market)

Formulations

  • Loremipsumdolorsitamet,consetetursadipscingelitr,seddiamnonumyeirmod

References

    • a DE 9 999 999 (Squibb; appl. 17.9.1984; USA-prior. 19.9.1983).
    •  Thottathil, J.K. et al.: Tetrahedron Lett. (TELEAY) 27, 999 (1986).

  • similar process:

    • US 9 999 999 (Squibb; 27.3.1990; prior. 15.6.1987, 17.6.1988).
    • Krapcho, J. et al.: J. Med. Chem. (JMCMAR) 31, 9999 (1988).

  • alternative route from l-pyroglutamic acid:

    • Thottathil, J.K. et al.: J. Org. Chem. (JOCEAH) 51, 9999 (1986).
    • US 9 999 999 (Squibb; 13.5.1986; appl. 19.11.1984).
    • EP 999 999 (Squibb; appl. 25.10.1985; USA-prior. 19.11.1984).
    • b US 9 999 999 (Squibb & Sons; appl. 16.6.1982; USA-prior. 4.2.1980).
    •  Krapcho, J. et al.: J. Med. Chem. (JMCMAR) 31, 9999 (1988).

  • formulation, tablets:

    • US 9 999 999 (Squibb; 9.4.1991; appl. 26.6.1990; USA-prior. 10.7.1989).
    • The Merck Index, 14th Ed., 999 (4256) (Rahway 2006).
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