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Infigratinib
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Synonyms:
NVP-BGJ398; BGJ-398
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ATC:
L01EN03
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Use:
Lorem
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Chemical name:
Lorem ipsum dolor sit amet, consetetur sadipscing elitr, sed diam
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Formula:
Lorem ipsum dolor sit amet,
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MW:560.5 g/mol
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CAS-RN:872511-34-7
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InChI Key:QADPYRIHXKWUSV-UHFFFAOYSA-N
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InChI:InChI=1S/C26H31Cl2N7O3/c1-5-34-10-12-35(13-11-34)18-8-6-17(7-9-18)31-21-15-22(30-16-29-21)33(2)26(36)32-25-23(27)19(37-3)14-20(38-4)24(25)28/h6-9,14-16H,5,10-13H2,1-4H3,(H,32,36)(H,29,30,31)
Derivatives
Phosphate
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Formula:
C26H31Cl2N7O3 • H3PO4
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MW:658.5 g/mol
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CAS-RN:1310746-10-1
Hydrochloride
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Formula:
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MW:
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CAS-RN:1310746-15-6
Mesylate
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Formula:
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MW:
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CAS-RN:1310746-13-3
Acetate
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Formula:
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MW:
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CAS-RN:1310746-17-8
Synthesis Path
Substances Referenced in Synthesis Path
| CAS-RN |
Formula |
Chemical Name |
CAS Index Name |
| 5308-25-8 |
C6H14N2 |
1-Ethylpiperazine |
|
| 586-78-7 |
C6H4BrNO2 |
1-bromo-4-nitrobenzene |
|
| 115619-01-7 |
C12H19N3 |
4-(4-ethylpiperazin-1-yl)-phenylamine |
|
| 65766-32-7 |
C5H6ClN3 |
(6-chloro-pyrimidin-4-yl)-methylamine |
|
| Lorem |
Lorem |
Lorem |
Lorem |
| Lorem |
Lorem |
Lorem |
Lorem |
| Lorem |
Lorem |
Lorem |
Lorem |
Trade Names
| Country |
Trade Name |
Vendor |
Annotation |
| USA |
Lorem |
Lorem
|
|
(wfm = withdrawn from market)
Formulations
- Loremipsumdolorsitamet,consetetursadipscingelitr,
References
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- a) Guagnano, V. et al., J. Med. Chem., (2011) 54, 7066-7083.
- US 9 999 999 (Novartis; 8.10.2013; appl. 23.6.2005; USA-prior. 24.6.2004).
- b) US 9 999 999 (Novartis; 30.6.2015; appl. 9.6.2012; USA-prior. 7.12.2009).
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Pharmaceutical dosage forms:
- US 99 999 999 (Novartis; 7.5.2019; appl. 11.12.2014; USA-prior. 13.12.2013).
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Methods for treating urinary system cancers:
- WO 9999 999999 (QED Therapeutics; 3.12.2020; appl. 29.5.2020; USA-prior. 31.5.2019).
