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Mifepristone
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Synonyms:
RU-486
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ATC:
G03XB01
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Use:
Lorem
Lorem
Lorem
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Chemical name:
Lorem ipsum dolor sit amet, consetetur sadipscing elitr, sed diam
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Formula:
Lorem ipsum dolor sit amet,
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MW:429.60 g/mol
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CAS-RN:84371-65-3
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InChI Key:VKHAHZOOUSRJNA-GCNJZUOMSA-N
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InChI:InChI=1S/C29H35NO2/c1-5-15-29(32)16-14-26-24-12-8-20-17-22(31)11-13-23(20)27(24)25(18-28(26,29)2)19-6-9-21(10-7-19)30(3)4/h6-7,9-10,17,24-26,32H,8,11-14,16,18H2,1-4H3/t24-,25+,26-,28-,29-/m0/s1
Substances Referenced in Synthesis Path
| CAS-RN |
Formula |
Chemical Name |
CAS Index Name |
| 7353-91-5 |
C8H10BrMgN |
4-dimethylaminophenylmagnesium bromide |
Magnesium, bromo[4-(dimethylamino)phenyl]- |
| 5173-46-6 |
C18H22O2 |
estra-4,9-diene-3,17-dione |
Estra-4,9-diene-3,17-dione |
| 5571-36-8 |
C20H26O3 |
3,3-(ethylenedioxy)estra-5(10),9(11)-dien-17-one |
Estra-5(10),9(11)-diene-3,17-dione, cyclic 3-(1,2-ethanediyl acetal) |
| 84371-57-3 |
C23H30O4 |
3,3-(ethylenedioxy)-17α-(1-propynyl)-5α,10α-epoxyestr-9(11)-en-17β-ol |
Estr-9(11)-en-3-one, 5,10-epoxy-17-hydroxy-17-(1-propynyl)-, cyclic 1,2-ethanediyl acetal, (5α,10α,17β)- |
| Lorem |
Lorem |
Lorem |
Lorem |
| Lorem |
Lorem |
Lorem |
Lorem |
Trade Names
| Country |
Trade Name |
Vendor |
Annotation |
| D |
Lorem |
Lorem
|
|
| F |
Lorem |
Lorem
|
|
| GB |
Lorem |
Lorem
|
|
(wfm = withdrawn from market)
References
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- EP 99 999 (Roussel-Uclaf; appl. 8.1.1982; F-prior. 9.1.1981).
- US 9 999 999 (Roussel-Uclaf; 31.5.1983; appl. 10.6.1982; F-prior. 9.1.1981).
- US 9 999 999 (Roussel-Uclaf; 8.5.1984; appl. 10.6.1982; F-prior. 9.1.1981).
- US 9 999 999 (Roussel-Uclaf; 28.5.1985; appl. 25.5.1984; prior. 9.1.1982, 10.6.1982, 30.3.1984; F-prior. 9.1.1981).
- US 9 999 999 (Roussel-Uclaf; 6.1.1987; appl. 22.1.1985; prior. 9.1.1982, 25.5.1984, 10.6.1982, 30.3.1984; F-prior. 9.1.1981).
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synthesis of 3,3-(ethylenedioxy)estra-5(10),9(11)-dien-17-one:
- BE 999 999 (Merck & Co.; appl. 1964).
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alternative synthesis:
- FR 9 999 999 (Roussel-Uclaf; appl. 1962).
- NL 9 999 999 (Roussel-Uclaf; appl. 1964; F-prior. 1963).
- BE 999 999 (Merck & Co.; appl. 1964).
