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Nitrazepam

  • ATC: N05CD02
  • Use: Lorem  Lorem 
  • Chemical name: Lorem ipsum dolor sit amet, consetetur sadipscing elitr, sed diam
  • Formula: Lorem ipsum dolor sit amet,
  • MW:281.27 g/mol
  • CAS-RN:146-22-5
  • InChI Key:KJONHKAYOJNZEC-UHFFFAOYSA-N
  • InChI:InChI=1S/C15H11N3O3/c19-14-9-16-15(10-4-2-1-3-5-10)12-8-11(18(20)21)6-7-13(12)17-14/h1-8H,9H2,(H,17,19)
  • EINECS:205-665-2
  • LD50: 130 mg/kg (M, i.v.); 550 mg/kg (M, p.o.);
    825 mg/kg (R, p.o.)

Substance Classes

Synthesis Path










Substances Referenced in Synthesis Path

CAS-RN Formula Chemical Name CAS Index Name
2835-77-0 C13H11NO 2-aminobenzophenone Methanone, (2-aminophenyl)phenyl-
1775-95-7 C13H10N2O3 2-amino-5-nitrobenzophenone Methanone, (2-amino-5-nitrophenyl)phenyl-
24042-91-9 C20H16N2O5S N-(2-benzoyl-4-nitrophenyl)-4-methylbenzenesulfonamide Benzenesulfonamide, N-(2-benzoyl-4-nitrophenyl)-4-methyl-
34052-37-4 C13H8ClNO3 2-chloro-5-nitrobenzophenone Methanone, (2-chloro-5-nitrophenyl)phenyl-
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem

Trade Names

Country Trade Name Vendor Annotation
D Lorem Lorem
Lorem Lorem
Lorem Lorem
Lorem Lorem Lorem
Lorem Lorem
Lorem Lorem
F Lorem Lorem
GB Lorem ipsum
I Lorem Lorem
J Lorem Lorem
Lorem Lorem
USA Lorem Lorem wfm
(wfm = withdrawn from market)

Formulations

  • Loremipsumdolorsitamet,consetetursadipscingelitr,seddiamnonumyeirmodtemporinviduntutlaboreetdolore

References

    • Sternbach, L.H. et al.: J. Med. Chem. (JMCMAR) 6, 261 (1963).
    • US 9 999 999 (Hoffmann-La Roche; 5.11.1963; appl. 21.6.1962; prior. 28.7.1961, 4.12.1961).
    • US 9 999 999 (Hoffman-La Roche; 31.12.1963; prior. 14.3.1962).
    • US 9 999 999 (Hoffman-La Roche; 3.3.1964; prior. 9.3.1962).
    • DE 9 999 999 (Hoffman-La Roche; appl. 7.12.1960; USA-prior. 10.12.1959, 27.6.1960).
    • DE 9 999 999 (Hoffman-La Roche; appl. 7.12.1960; USA-prior. 10.12.1959, 15.1.1960, 26.4.1960, 27.6.1960).
    • DAS 9 999 999 (Delmar Chemicals; appl. 29.11.1968; CDN-prior. 29.11.1967).
  • condensation of 2-aminobenzophenone with glycine and POCl3/nitrobenzene and following nitration with KNO3/H2SO4:

    • DOS 9 999 999 (Roche; appl. 25.10.1972; CH-prior. 18.11.1971).
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