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Osilodrostat
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Synonyms:
LCI-699
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ATC:
H02CA02
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Use:
Lorem
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Chemical name:
Lorem ipsum dolor sit amet, consetetur sadipscing elitr, sed diam
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Formula:
Lorem ipsum dolor sit amet,
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MW:227.24 g/mol
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CAS-RN:928134-65-0
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InChI Key:USUZGMWDZDXMDG-CYBMUJFWSA-N
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InChI:InChI=1S/C13H10FN3/c14-12-5-9(6-15)1-3-11(12)13-4-2-10-7-16-8-17(10)13/h1,3,5,7-8,13H,2,4H2/t13-/m1/s1InChI=1S/C13H10FN3/c14-12-5-9(6-15)1-3-11(12)13-4-2-10-7-16-8-17(10)13/h1,3,5,7-8,13H,2,4H2/t13-/m1/s1
Derivatives
Phosphate
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Formula:
C13H10FN3 • H3PO4
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MW:325.24 g/mol
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CAS-RN:1315449-72-9
Synthesis Path
Substances Referenced in Synthesis Path
| CAS-RN |
Formula |
Chemical Name |
CAS Index Name |
| 170572-49-3 |
C8H6FN |
3-fluoro-4-methylbenzonitrile |
|
| 105942-09-4 |
C8H5BrFN |
4-bromomethyl-3-fluoro-benzonitrile |
|
| 645-65-8 |
C5H6N2O2 |
(1H-imidazol-4-yl)-acetic acid |
|
|
C24H20N2O2 |
2-(1-trityl-1H-imidazol-4-yl)-acetic acid |
|
| Lorem |
Lorem |
Lorem |
Lorem |
| Lorem |
Lorem |
Lorem |
Lorem |
| Lorem |
Lorem |
Lorem |
Lorem |
Trade Names
| Country |
Trade Name |
Vendor |
Annotation |
| USA |
Lorem |
Lorem
|
|
| EU |
Lorem |
Lorem
|
|
(wfm = withdrawn from market)
Formulations
- Loremipsumdolorsitamet,consetetursadipscingelitr,sed
References
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- Meredith, E.L. et al., ACS Med. Chem. Lett., (2013) 4, 1203-1207 and Suppl. Material.
- Papillon, J.P.N. et al., J. Med. Chem., (2015) 58, 4749-4770.
- US 9 999 999 (Novartis; 20.11.2012; USA-prior. 25.08.2005).
- US 9 999 999 (Novartis; 16.09.2014; USA-prior. 25.08.2005).
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Med. Use:
- US 9 999 999 (Novartis; 17.12.2013; USA-prior. 14.01.2010).
- US 9 999 999 (Novartis; 06.09.2016; USA-prior. 14.01.2010).
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Polymorphs and salts:
- WO 9999 999999 A1 (Novartis; publ. 25.07.2013 ; USA-prior. 17.01.2012).
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Formulation:
- US 99 999 999 (Novartis; 04.12.2018 ; USA-prior. 07.07.2014).
- US 99 999 999 (Recordati; 14.07.2020; USA-prior. 07.07.2014).
