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Pimobendan
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Synonyms:
UD-CG 115, UD-CG 115BS
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ATC:
C01CE
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Use:
Lorem
Lorem
Lorem
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Chemical name:
Lorem ipsum dolor sit amet, consetetur sadipscing elitr, sed diam
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Formula:
Lorem ipsum dolor sit amet,
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MW:334.38 g/mol
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CAS-RN:74150-27-9
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InChI Key:GLBJJMFZWDBELO-UHFFFAOYSA-N
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InChI:InChI=1S/C19H18N4O2/c1-11-9-17(24)22-23-18(11)13-5-8-15-16(10-13)21-19(20-15)12-3-6-14(25-2)7-4-12/h3-8,10-11H,9H2,1-2H3,(H,20,21)(H,22,24)
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LD50:>2 g/kg (M, p.o.);
72 mg/kg (R, i.v.); 950 mg/kg (R, p.o.)
Derivatives
hydrochloride
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Use:
-
Formula:
Lorem ipsum dolor sit amet,
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MW:unspecified
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CAS-RN:74149-75-0
monohydrochloride
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Use:
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Formula:
Lorem ipsum dolor sit amet,
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MW:370.84 g/mol
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CAS-RN:77469-98-8
racemate
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Use:
-
Formula:
Lorem ipsum dolor sit amet,
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MW:334.38 g/mol
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CAS-RN:118428-36-7
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LD50:75 mg/kg (R, i.v.)
(–)-enantiomer
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Use:
-
Formula:
Lorem ipsum dolor sit amet,
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MW:334.38 g/mol
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CAS-RN:118428-37-8
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LD50:100 mg/kg (R, i.v.)
(+)-enantiomer
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Use:
-
Formula:
Lorem ipsum dolor sit amet,
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MW:334.38 g/mol
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CAS-RN:118428-38-9
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LD50:75 mg/kg (R, i.v.)
Substances Referenced in Synthesis Path
CAS-RN |
Formula |
Chemical Name |
CAS Index Name |
100-07-2 |
C8H7ClO2 |
4-anisoyl chloride |
Benzoyl chloride, 4-methoxy- |
74149-73-8 |
C19H18N4O5 |
4,5-dihydro-6-[4-(4-methoxybenzoylamino)-3-nitrophenyl]-5-methyl-3(2H)-pyridazinone |
Benzamide, 4-methoxy-N-[2-nitro-4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl]- |
7803-57-8 |
H6N2O |
hydrazine hydrate |
Hydrazine, monohydrate |
74149-71-6 |
C12H14N2O5 |
methyl 3-(4-amino-3-nitrobenzoyl)butyrate |
Benzenebutanoic acid, 4-amino-β-methyl-3-nitro-γ-oxo-, methyl ester |
Lorem |
Lorem |
Lorem |
Lorem |
Trade Names
Country |
Trade Name |
Vendor |
Annotation |
J |
Lorem |
Lorem
|
|
(wfm = withdrawn from market)
References
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- EP 9 999 (Thomae GmbH; appl. 3.2.1980; D-prior. 25.8.1978, 1.6.1979).
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separation of enantiomers:
- DE 9 999 999 (Thomae GmbH; appl. 25.8.1987; D-prior. 25.8.1987).
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oral formulation:
- DE 9 999 999 (Thomae GmbH; appl. 20.1.1990; D-prior. 20.1.1990).
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use for treatment of asthma:
- DE 9 999 999 (Thomae GmbH; appl. 20.1.1990; D-prior. 20.1.1990).
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combination with β-blockers:
- EP 999 999 (Thomae GmbH; appl. 12.3.1990; D-prior. 16.3.1989).
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use for treating erectile dysfunction:
- DE 9 999 999 (J. Carlen; appl. 15.11.1993; D-prior. 15.11.1993).