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Prucalopride
  • Synonyms: R-93877; R-108512
  • ATC: A06AX05
  • Use: Lorem 
  • Chemical name: Lorem ipsum dolor sit amet, consetetur sadipscing elitr, sed diam
  • Formula: Lorem ipsum dolor sit amet,
  • MW:367.87 g/mol
  • CAS-RN:179474-81-8
  • InChI Key:ZPMNHBXQOOVQJL-UHFFFAOYSA-N
  • InChI:InChI=1S/C18H26ClN3O3/c1-​24-​9-​2-​6-​22-​7-​3-​12(4-​8-​22)​21-​18(23)​14-​11-​15(19)​16(20)​13-​5-​10-​25-​17(13)​14/h11-​12H,​2-​10,​20H2,​1H3,​(H,​21,​23)

Derivatives

    Succinate:

  • Formula: C18H26ClN3O3 • C4H6O4
  • MW:486 g/mol
  • CAS-RN:179474-85-2

Substance Classes

Synthesis Path

Substances Referenced in Synthesis Path

CAS-RN Formula Chemical Name CAS Index Name
4093-28-1 C10H11NO4 methyl 4-acetamido-salicylate
24190-77-0 C10H10ClNO4 methyl 4-acetamido-5-chloro-salicylate
114971-52-7 C10H16Cl2IN benzyltrimethylammoniumiododichloride
143878-24-4 C10H9ClINO4 methyl 4-acetamido-5-chloro-3-iodo-salicylate
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem

Trade Names

Country Trade Name Vendor Annotation
EU Lorem Lorem
USA Lorem Lorem
(wfm = withdrawn from market)

Formulations

  • Loremipsumdolorsitamet,

References

    • US 9 999 999 (Janssen; 09.02.1993; GB-prior. 06.03.1990).
    • US 9 999 999 (Janssen; 29.12.1998; EP-prior. 24.11.1994).
    • US 9 999 999 (Janssen; 07.09.1999; EP-prior. 24.11.1994).
    • US 9 999 999 (Janssen; 30.10.2001; EP-prior. 23.11.1994) - salt preparations.
    • WO 9999 999999 (Symed Labs.; publ. 17.08.2017; IN-prior. 11.02.2016). - processes.

  • Synthesis of intermediate methyl 4-acetamido-5-chloro-2,3-dihydrobenzo[b]furan-7-carboxylate:

    • US 9 999 999 (Farmitalia Carlo Erba; 17.10.1995; GB-prior. 27.12.1990).
    • EP 999 999 (Janssen; 26.09.1990; USA-prior. 22.03.1989).
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