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Pexidartinib

  • Synonyms: PLX-3397
  • ATC: L01EX15
  • Use: Lorem 
  • Chemical name: Lorem ipsum dolor sit amet, consetetur sadipscing elitr, sed diam
  • Formula: Lorem ipsum dolor sit amet,
  • MW:417.8 g/mol
  • CAS-RN:1029044-16-3
  • InChI Key:JGWRKYUXBBNENE-UHFFFAOYSA-N
  • InChI:InChI=1S/C20H15ClF3N5/c21-15-6-16-14(10-28-19(16)29-11-15)5-12-2-4-18(26-7-12)27-9-13-1-3-17(25-8-13)20(22,23)24/h1-4,6-8,10-11H,5,9H2,(H,26,27)(H,28,29)

Derivatives

    Hydrochloride

  • Formula: C20H15ClF3N5 • HCl
  • MW:454.3 g/mol
  • CAS-RN:2040295-03-0

Substance Classes

Synthesis Path










Substances Referenced in Synthesis Path

CAS-RN Formula Chemical Name CAS Index Name
80235-01-4 C7H5ClN2 3-chloro-7-azaindol
1072-97-5 C5H5BrN2 2-amino-5-bromopyridine
386704-12-7 C7H4F3NO 6-(trifluoromethyl)-pyridine-3-carbaldehyde
503039-05-2 C13H13BrN2O 5-Bromo-N-(4-methoxybenzyl)pyridin-2-amine
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem

Trade Names

Country Trade Name Vendor Annotation
USA Lorem Lorem
(wfm = withdrawn from market)

Formulations

  • Loremipsumdolorsitamet,consetetursadipscingelitr,seddiam

References

    • Lamb, Y.N., Drugs, (2019) 79 (16), 1805-1812.
    • c) Chen, D. et al., Synthesis, (2019) 51(12), 2564-2571.
    • a) US 9 999 999 (Plexxikon; 22.2.2011; appl. 21.11.2007; USA-prior. 22.11.2006).
    • b) US 9 999 999 (Daichi Sankyo/Plexxikon; 29.8.2017; appl. 5.5.2016; USA-prior. 6.5.2015).
    • US 9 999 999 (Plexxikon; 31.10.2017; appl. 5.5.2016; USA-prior. 6.5.2015).
    • US 99 999 999 (Daichi Sankyo/Plexxikon; 4.8.2000; appl. 12.7.2019; USA-prior. 6.5.2015).