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Ponesimod
-
Synonyms:
ACT-128000; RG-3477
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ATC:
L04AA50
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Use:
Lorem
-
Chemical name:
Lorem ipsum dolor sit amet, consetetur sadipscing elitr, sed diam
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Formula:
Lorem ipsum dolor sit amet,
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MW:461.0 g/mol
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CAS-RN:854107-55-4
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InChI Key:LPAUOXUZGSBGDU-STDDISTJSA-N
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InChI:InChI=1S/C23H25ClN2O4S/c1-3-10-25-23-26(19-7-5-4-6-15(19)2)22(29)21(31-23)12-16-8-9-20(18(24)11-16)30-14-17(28)13-27/h4-9,11-12,17,27-28H,3,10,13-14H2,1-2H3/b21-12-,25-23-/t17-/m1/s1
Substances Referenced in Synthesis Path
| CAS-RN |
Formula |
Chemical Name |
CAS Index Name |
| 614-69-7 |
C8H7NS |
o-tolyl-isothiocyanate |
|
| 107-10-8 |
C3H9N |
n-propylamine |
|
|
C13H16N2OS |
2-[(Z)-propylimino]-3-o-tolylthiazolidin-4-one |
|
|
C13H15ClO4 |
3-chloro-4-((4S)-2,2-dimethyl-[1,3]dioxolan-4-ylmethoxy)-benzaldehyde |
|
| Lorem |
Lorem |
Lorem |
Lorem |
| Lorem |
Lorem |
Lorem |
Lorem |
| Lorem |
Lorem |
Lorem |
Lorem |
| Lorem |
Lorem |
Lorem |
Lorem |
| Lorem |
Lorem |
Lorem |
Lorem |
Trade Names
| Country |
Trade Name |
Vendor |
Annotation |
| USA |
Lorem |
Lorem
|
|
| EU |
Lorem |
Lorem
|
|
(wfm = withdrawn from market)
Formulations
- Loremipsumdolorsitamet,consetetursadipscingelitr,seddiamnonumyeirmodtemporinviduntutlaboreetdoloremagnaaliquyamerat,sed
References
-
- a) Bolli, M. H. et al., J. Med. Chem., (2010) 53, 4198-4211.
- US 9 999 999 (Actelion Pharmas.; 25.9.2012; appl. 2.7.2009; EP-prior. 21.11.2003).
- b) WO 9999 999999 (Actelion Pharmas.; 20.2.2014; appl. 15.8.2013; EP-prior. 17.8.2012).
- c) WO 9999 999999 (Actelion Pharmas.; 29.5.2008; appl. 22.11.2007; IB-prior. 23.11.2006).
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Crystalline forms:
- US 9 999 999 (Actelion Pharmas.; 23.6.2015; appl. 19.10.2009; GB-prior. 20.10.2008).
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New crystalline polymorph:
- WO 9999 999999 (Teva Pharmas.; 28.3.2019; appl. 7.9.2018; IN-prior. 19.9.2017).
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Pharmaceutical combination:
- US 9999 999999 (Actelion Pharmas.; 13.6.2019; appl. 15.2.2019; EP-prior. 11.12.2014).
