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Plerixafor
  • Synonyms: AMD-3100; JM-3100
  • ATC: L03AX16
  • Use: Lorem 
  • Chemical name: Lorem ipsum dolor sit amet, consetetur sadipscing elitr, sed diam
  • Formula: Lorem ipsum dolor sit amet,
  • MW:502.80 g/mol
  • CAS-RN:110078-46-1
  • InChI Key:YIQPUIGJQJDJOS-UHFFFAOYSA-N
  • InChI:InChI=1S/C28H54N8/c1-​9-​29-​15-​17-​31-​13-​3-​21-​35(23-​19-​33-​11-​1)​25-​27-​5-​7-​28(8-​6-​27)​26-​36-​22-​4-​14-​32-​18-​16-​30-​10-​2-​12-​34-​20-​24-​36/h5-​8,​29-​34H,​1-​4,​9-​26H2

Derivatives

    Octahydrochloride

  • Formula: C28H54N8 • 8HCl
  • MW:794.46 g/mol
  • CAS-RN:155148-31-5

Substance Classes

Synthesis Path

Substances Referenced in Synthesis Path

CAS-RN Formula Chemical Name CAS Index Name
10563-26-5 C8H22N4 N,N'-bis-(3-aminopropyl)-ethylenediamine
6315-52-2 C16H18O6S2 ethyleneglycol ditosylate

Trade Names

Country Trade Name Vendor Annotation
USA Lorem Lorem
EU Lorem Lorem
(wfm = withdrawn from market)

Formulations

  • Loremipsumdolorsitamet,consetetursadipscingelitr,seddiam

References

    • Bridger, G.J. et al., J. Med. Chem., (1995) 38, 366-378.
    • US 9 999 999 (Johnson Matthey; 1997; USA-prior. 1995).
    • US 9 999 999 (Johnson Matthey; 1997; USA-prior. 1995).
    • US 9 999 999 (Johnson Matthey; 1998; USA-prior. 1995).
    • US 9 999 999 (Anormed; 17.01.2006; USA-prior. 31.07.2001).
    • US 9 999 999 (Genzyme; 01.03.2011; USA-prior. 31.07.2001).

  • Alternative synthesis without protecting groups:

    • Achmatowicz, M. and Hegedus, L.S., J.Org. Chem., (2003) 68, 6435-6436.

  • History:

    • De Clercq, "The bicyclam AMD3100 story", Nature Reviews Drug Discovery, (2003) 2, 581-587.
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