Please log in to see the full text of this API!
Romidepsin
-
Synonyms:
FK228; FR901228
-
ATC:
L01XH02
-
Use:
Lorem
-
Chemical name:
Lorem ipsum dolor sit amet, consetetur sadipscing elitr, sed diam
-
Formula:
Lorem ipsum dolor sit amet,
-
MW:540.7 g/mol
-
CAS-RN:128517-07-7
-
InChI Key:OHRURASPPZQGQM-GCCNXGTGSA-N
-
InChI:InChI=1S/C24H36N4O6S2/c1-6-16-21(30)28-20(14(4)5)24(33)34-15-9-7-8-10-35-36-12-17(22(31)25-16)26-23(32)19(13(2)3)27-18(29)11-15/h6-7,9,13-15,17,19-20H,8,10-12H2,1-5H3,(H,25,31)(H,26,32)(H,27,29)(H,28,30)/b9-7+,16-6-/t15-,17-,19-,20+/m1/s1
Substances Referenced in Synthesis Path
| CAS-RN |
Formula |
Chemical Name |
CAS Index Name |
|
C25H30N2O6 |
Fmoc-L-Thr-L-Val-OMe |
|
|
C52H56N4O7S |
N-α-[(Fluorenylmethoxy)-carbonyl]-D-Valyl-D-Cysteinyl-(S-triphenylmethyl)-(Z)-dehydrobutyrinyl-L-Valine methyl ester |
|
|
|
D-Valyl-D-Cysteinyl-(S-triphenylmethyl)-(Z)-dehydrobutyrinyl-L-Valine methyl ester |
|
| 180973-26-6 |
C26H26O3S |
(R,E)-3-hydroxy-7-(tritylthio)-hept-4-enoic acid |
|
| Lorem |
Lorem |
Lorem |
Lorem |
| Lorem |
Lorem |
Lorem |
Lorem |
| Lorem |
Lorem |
Lorem |
Lorem |
| Lorem |
Lorem |
Lorem |
Lorem |
| Lorem |
Lorem |
Lorem |
Lorem |
| Lorem |
Lorem |
Lorem |
Lorem |
Trade Names
| Country |
Trade Name |
Vendor |
Annotation |
| USA |
Lorem |
Lorem
|
|
(wfm = withdrawn from market)
References
-
- a Ueda, H. et al., J. Antibiot., (1994) 47, 301-310.
- b Greshock, T. J. et al., Org. Lett., (2008) 10, 613-616.
- c Narita, K. et al., Chem. Eur. J., (2009) 15(42), 11174-11186.
- d Li, K. W. et al., JACS, (1996) 118(30), 7237.
- US 9 999 999 (Fujisawa Pharm.; 11.12.1990; appl. 6.7.1989; GB-prior. 26.7.1988).
- US 9 999 999 (Astellas Pharm.; 3.11.2009; appl. 3.3.2009; JP-prior. 22.8.2001).
-
sequences for FK228 biosynthesis:
- US 9 999 999 (UWM Res. Foundation; 3.4.2012; appl. 8.2.2008; USA-prior. 7.2.2007).
