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Sorafenib

  • Synonyms: Bay 43-9006
  • ATC: L01EX02
  • Use: Lorem  Lorem 
  • Chemical name: Lorem ipsum dolor sit amet, consetetur sadipscing elitr, sed diam
  • Formula: Lorem ipsum dolor sit amet,
  • MW:464.83 g/mol
  • CAS-RN:284461-73-0
  • InChI Key:MLDQJTXFUGDVEO-UHFFFAOYSA-N
  • InChI:InChI=1S/C21H16ClF3N4O3/c1-26-19(30)18-11-15(8-9-27-18)32-14-5-2-12(3-6-14)28-20(31)29-13-4-7-17(22)16(10-13)21(23,24)25/h2-11H,1H3,(H,26,30)(H2,28,29,31)

Derivatives

    monotosylate

  • Formula: C28H24ClF3N4O6S
  • MW:637.04 g/mol
  • CAS-RN:475207-59-1

Substance Classes

Synthesis Path








Substances Referenced in Synthesis Path

CAS-RN Formula Chemical Name CAS Index Name
284462-37-9 C13H13N3O2 4-(4-aminophenoxy)-N-methyl-2-pyridinecarboxamide
530-62-1 C7H6N4O 1,1'-carbonyldiimidazole 1H-Imidazole, 1,1'-carbonylbis-
220000-87-3 C7H7ClN2O 4-chloro-N-methyl-2-pyridinecarboxamide
320-51-4 C7H5ClF3N 4-chloro-3-(trifluoromethyl)aniline
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Trade Names

Country Trade Name Vendor Annotation
D Lorem Lorem ,2006
F Lorem Lorem
GB Lorem Lorem ,2006
I Lorem Lorem ,2006
USA Lorem Lorem ,2005
(wfm = withdrawn from market)

Formulations

  • Lorem

References

    • a, b Bankston, D. et al.: Org. Process Res. Dev. (OPRDFK) 6, 777-781 (2002).
    •  US 9 999 999 (Bayer; 26.6.2007; USA-prior. 12.1.2001, 11.1.2002).
    •  US 9 999 999 (Bayer; 13.5.2008; USA-prior. 20.4.2001, 19.4.2002).
    •  WO 9 999 999 999 (Bayer Corp.; 20.7.2000; appl. 13.1.2000; USA-prior. 13.1.1999).
    •  WO 9 999 999 999 (Bayer Corp.; 10.10.2002; appl. 7.2.2002; USA-prior. 13.1.1999).
    •  US 9 999 999 999 (Bayer Corp.; 20.11.2003; appl. 11.2.2003; USA-prior. 11.2.2002).
    •  WO 9 999 999 999 (Bayer Corp.; 29.12.2004; appl. 19.5.2004; USA-prior. 20.5.2003).
    •  WO 9 999 999 999 (Bayer Corp.; 6.1.2005; appl. 19.5.2004; USA-prior. 20.5.2003).
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