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Selumetinib
  • Synonyms: AZD6244; ARRY-142886
  • ATC: L01EE04
  • Use: Lorem 
  • Chemical name: Lorem ipsum dolor sit amet, consetetur sadipscing elitr, sed diam
  • Formula: Lorem ipsum dolor sit amet,
  • MW:457.7 g/mol
  • CAS-RN:606143-52-6
  • InChI Key:CYOHGALHFOKKQC-UHFFFAOYSA-N
  • InChI:InChI=1S/C17H15BrClFN4O3/c1-​24-​8-​21-​16-​13(24)​7-​10(17(26)​23-​27-​5-​4-​25)​15(14(16)​20)​22-​12-​3-​2-​9(18)​6-​11(12)​19/h2-​3,​6-​8,​22,​25H,​4-​5H2,​1H3,​(H,​23,​26)

Derivatives

    Sulfate

  • Formula: C17H17BrClFN4O7S
  • MW:555.8 g/mol
  • CAS-RN:943332-08-9

Substance Classes

Synthesis Path



Substances Referenced in Synthesis Path

CAS-RN Formula Chemical Name CAS Index Name
61079-72-9 C7H3F3O2 2,3,4-trifluorobenzoic acid
197520-71-1 C7H2F3NO4 2,3,4-trifluoro-5-nitro-benzoic acid
284030-57-5 C7H4N2O4 4-amino-2,3-difluoro-5-nitro-benzoic acid
284030-58-6 C8H6F2N2O4 4-amino-2,3-difluoro-5-nitro-benzoic acid methyl ester
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem

Trade Names

Country Trade Name Vendor Annotation
USA Lorem Lorem
(wfm = withdrawn from market)

Formulations

  • Loremipsumdolorsitamet,consetetursadipscingelitr,sed

References

    • Dombi, E. et al., N. Engl. J. Med., (2016) 375(26),2550-2560.
    • US 9 999 999 (Array Biopharma; 16.9.2008; appl. 18.2.2005; USA-prior. 13.3.2003).
    • US 9 999 999 (Array Biopharma; 15.5.2012; appl. 28.6.2010; USA-prior. 13.3.2002).
    • US 9 999 999 (Array Biopharma; 13.10.2015; appl. 3.5.2012; USA-prior. 21.12.2005).
    • US 9 999 999 (Array Biopharma/AstraZeneca; 7.2.2017; appl. 28.4.2015; USA-prior. 21.12.2005).
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