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Teniposide

  • ATC: L01CB02
  • Use: Lorem 
  • Chemical name: Lorem ipsum dolor sit amet, consetetur sadipscing elitr, sed diam
  • Formula: Lorem ipsum dolor sit amet,
  • MW:656.66 g/mol
  • CAS-RN:29767-20-2
  • InChI Key:NRUKOCRGYNPUPR-ANTWWVKXSA-N
  • InChI:InChI=1S/C32H32O13S/c1-​37-​19-​6-​13(7-​20(38-​2)​25(19)​33)​23-​14-​8-​17-​18(42-​12-​41-​17)​9-​15(14)​28(16-​10-​39-​30(36)​24(16)​23)​44-​32-​27(35)​26(34)​29-​21(43-​32)​11-​40-​31(45-​29)​22-​4-​3-​5-​46-​22/h3-​9,​16,​21,​23-​24,​26-​29,​31-​35H,​10-​12H2,​1-​2H3/t16-,​21?,​23+,​24-,​26?,​27?,​28+,​29?,​31+,​32?/m0/s1
  • EINECS:249-831-2
  • LD50:29.57 mg/kg (M, i.p.); 31.56 mg/kg (M, s.c.)

Substance Classes

Synthesis Path








Substances Referenced in Synthesis Path

CAS-RN Formula Chemical Name CAS Index Name
501-53-1 C8H7ClO2 benzyl chloroformate Carbonochloridic acid, phenylmethyl ester
23363-33-9 C29H26O10 4'-benzyloxycarbonyl-4'-demethylepipodophyllotoxin Carbonic acid, 4-(5,5a,6,8,8a,9-hexahydro-9-hydroxy-6-oxofuro[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-5-yl)-2,6-dimethoxyphenyl phenylmethyl ester, [5R-(5α,5aβ,8aα,9β)]-
23362-12-1 C43H44O19 [5R-(5α,5aβ,8aα,9β)]-carbonic acid 4-[5,5a,6,8,8a,9-hexahydro-6-oxo-9-[(2,3,4,6-tetra-O-acetyl-β-d-glucopyranosyl)oxy]furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-5-yl]-2,6-dimethoxyphenyl phenylmethyl ester Carbonic acid, 4-[5,5a,6,8,8a,9-hexahydro-6-oxo-9-[(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)oxy]furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-5-yl]-2,6-dimethoxyphenyl phenylmethyl ester, [5R-(5α,5aβ,8aα,9β)]-
501-53-1 C8H7ClO2 Cbo-Cl Carbonochloridic acid, phenylmethyl ester
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Trade Names

Country Trade Name Vendor Annotation
D Lorem Lorem
F Lorem Lorem wfm
I Lorem Lorem
USA Lorem Lorem
(wfm = withdrawn from market)

Formulations

  • Loremipsumdolor

References

    • DOS 9 999 999 (Sandoz; appl. 10.12.1966; CH-prior. 14.12.1966, 12.10.1966, 14.12.1965).
    • Keller-Juslen, C. et al.: J. Med. Chem. (JMCMAR) 14, 999 (1971).
    • FR 9 999 999 (Sandoz AG; appl. 15.6.1967; CH-prior. 12.10.1966, 14.12.1965).
  • toxicity reduction by addition of lithium carbonate:

    • FR 9 999 999 (Sandoz; appl. 6.8.1975).
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