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Tenofovir disoproxil fumarate
  • Synonyms: GS-4331-05, bis(POC)PMPA
  • ATC: J05AF07
  • Use: Lorem  Lorem  Lorem 
  • Chemical name: Lorem ipsum dolor sit amet, consetetur sadipscing elitr, sed diam
  • Formula: Lorem ipsum dolor sit amet,
  • MW:635.52 g/mol
  • CAS-RN:202138-50-9
  • InChI Key:VCMJCVGFSROFHV-WZGZYPNHSA-N
  • InChI:InChI=1S/C19H30N5O10P.C4H4O4/c1-​12(2)​33-​18(25)​28-​9-​31-​35(27,​32-​10-​29-​19(26)​34-​13(3)​4)​11-​30-​14(5)​6-​24-​8-​23-​15-​16(20)​21-​7-​22-​17(15)​24;5-​3(6)​1-​2-​4(7)​8/h7-​8,​12-​14H,​6,​9-​11H2,​1-​5H3,​(H2,​20,​21,​22);1-​2H,​(H,​5,​6)​(H,​7,​8)/b;2-​1+/t14-​;/m1./s1

Derivatives

    base

  • Use:
  • Formula: Lorem ipsum dolor sit amet,
  • MW:519.45 g/mol
  • CAS-RN:201341-05-1

Substance Classes

Synthesis Path















Substances Referenced in Synthesis Path

CAS-RN Formula Chemical Name CAS Index Name
73-24-5 C5H5N5 adenine 1H-Purin-6-amine
98-88-4 C7H5ClO benzoyl chloride Benzoyl chloride
35717-98-7 C14H23O6PS [bis(1-methylethoxy)phosphono]methyl 4-methylbenzenesulfonate Phosphonic acid, [[[(4-methylphenyl)sulfonyl]oxy]methyl]-, bis(1-methylethyl) ester
C22H30N5O5P bis(1-methylethyl) [[[(1R)-2-(6-benzoylamino)-9H-purin-9-yl]-1-methylethoxy]methyl]phosphonate
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem

Trade Names

Country Trade Name Vendor Annotation
D Lorem Lorem comb.
Lorem Lorem
F Lorem Lorem comb.
Lorem Lorem
GB Lorem Lorem
I Lorem Lorem
J Lorem Lorem Lorem comb. with emtricitabine
Lorem Lorem Lorem
USA Lorem Lorem comb.
Lorem Lorem comb.
Lorem Lorem
(wfm = withdrawn from market)

Formulations

  • Loremipsumdolor

References

    • a WO 9 999 999 (Gilead Sciences; 5.2.1998; appl. 25.7.1997; USA-prior. 26.7.1996).
    •  Holy, A. et al.: Collect. Czech. Chem. Commun. (CCCCAK) 60, 9999 (1995).
    • b US 9 999 999 (Gilead Sciences; 10.8.1999; appl. 25.7.1997).
    •  Schultze, L. M. et al.: Tetrahedron Lett. (TELEAY) 39, 9999 (1998).
    •  Chapman, H. et al.: Nucleosides, Nucleotides, Nucleic acids (NNNAFY) 20, 999 (2001).
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