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Trilaciclib
  • Synonyms: G1T28
  • ATC: V03AF12
  • Use: Lorem 
  • Chemical name: Lorem ipsum dolor sit amet, consetetur sadipscing elitr, sed diam
  • Formula: Lorem ipsum dolor sit amet,
  • MW:446.6 g/mol
  • CAS-RN:1374743-00-6
  • InChI Key:PDGKHKMBHVFCMG-UHFFFAOYSA-N
  • InChI:InChI=1S/C24H30N8O/c1-​30-​9-​11-​31(12-​10-​30)​18-​5-​6-​20(25-​15-​18)​28-​23-​26-​14-​17-​13-​19-​22(33)​27-​16-​24(7-​3-​2-​4-​8-​24)​32(19)​21(17)​29-​23/h5-​6,​13-​15H,​2-​4,​7-​12,​16H2,​1H3,​(H,​27,​33)​(H,​25,​26,​28,​29)

Derivatives

    Dihydrochloride

  • Formula: C24H30N8O • 2HCl
  • MW:519.5 g/mol
  • CAS-RN:1977495-97-8

Substance Classes

Synthesis Path



Substances Referenced in Synthesis Path

CAS-RN Formula Chemical Name CAS Index Name
36082-50-5 C4HBrCl2N2 5-bromo-2,4-dichloro-pyrimidine
C12H24N2O2 N1-(tert.butoxycarbonyl)-1-(aminomethyl)cyclohexan-1-amine
10160-87-9 C7H12O2 3,3-diethoxy-prop-1-yne
C16H24BrClN4O2 tert.butyl N-[[1-[(5-bromo-2-chloro-pyrimidin-4-yl)amino]cyclohexyl]methyl]carbamate
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem

Trade Names

Country Trade Name Vendor Annotation
USA Lorem Lorem
(wfm = withdrawn from market)

Formulations

  • Loremipsumdolorsitamet,consetetursadipscingelitr,seddiam

References

    • a) US 9 999 999 (G1 Therapeutics; 3.12.2013; appl. 24.4.2013; USA-prior. 25.10.2010).
    • WO 9999 999999 (G1 Therapeutics; 18.9.2014; appl. 14.3.2014; USA-prior. 15.3.2013).
    • US 99 999 999 (G1 Therapeutics; 19.3.2019; appl. 13.3.2017; USA-prior. 12.9.2014).
    • b) WO 9999 999999 (G1 Therapeutics; 4.1.2018; appl. 29.6.2017; USA-prior. 1.7.2016).
    • US 99 999 999 (G1 Therapeutics; 15.12.2020; appl. 21.12.2018; USA-prior. 1.7.2016).

  • Compositions and combinations:

    • WO 9999 99999 (Icahn School of Medicine; 14.6.2018; appl. 8.12.2017; USA-prior. 8.12.2016).
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