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Umbralisib
  • Synonyms: RP-5264; TGR-1202
  • ATC: L01EM
  • Use: Lorem 
  • Chemical name: Lorem ipsum dolor sit amet, consetetur sadipscing elitr, sed diam
  • Formula: Lorem ipsum dolor sit amet,
  • MW:571.56 g/mol
  • CAS-RN:1532533-67-7
  • InChI Key:IUVCFHHAEHNCFT-INIZCTEOSA-N
  • InChI:InChI=1S/C31H24F3N5O3/c1-​15(2)​41-​24-​9-​7-​18(12-​22(24)​34)​27-​26-​30(35)​36-​14-​37-​31(26)​39(38-​27)​16(3)​29-​25(17-​5-​4-​6-​19(32)​11-​17)​28(40)​21-​13-​20(33)​8-​10-​23(21)​42-​29/h4-​16H,​1-​3H3,​(H2,​35,​36,​37)/t16-​/m0/s1

Derivatives

    Tosylate:

  • Formula: C31H24F3N5O3 • C7H8O3S
  • MW:743.8 g/mol
  • CAS-RN:1532533-72-4

    Hydrochloride:

  • Formula: C31H24F3N5O3 • HCl
  • MW:608.0 g/mol
  • CAS-RN:n/a

Substance Classes

Synthesis Path






Substances Referenced in Synthesis Path

CAS-RN Formula Chemical Name CAS Index Name
331-25-9 C8H7FO2 3-fluorophenylacetic acid
79-37-8 C2Cl2O2 Oxalylchloride
459-60-9 C7H7FO 4-fluoroanisole
1300582-07-3 C14H10F2O2 1-(5-fluoro-2-hydroxyphenyl)-2-(3-fluorophenyl)-ethanone
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem

Trade Names

Country Trade Name Vendor Annotation
USA Lorem Lorem
(wfm = withdrawn from market)

Formulations

  • Loremipsumdolorsitamet,consetetursadipscing

References

    • Perry, M.W.D., J. Med. Chem., (2019) 62, 4783-4814.
    • EP 9 999 999 (Rhizen Pharmaceuticals; 30.08.2017; IN-prior. 04.07.2012; USA-prior. 21.08.2012).
    • EP 9 999 999 (Rhizen Pharmaceuticals; 20.03.2019; IN-prior. 04.07.2012; USA-prior. 21.08.2012).
    • US 9 999 999 (Rhizen Pharmaceuticals; 06.10.2015; IN-prior. 04.07.2012; USA-prior. 21.08.2012).
    • US 9 999 999 (Rhizen Pharmaceuticals; 06.06.2017; IN-prior. 04.07.2012; USA-prior. 21.08.2012).
    • US 9 999 999 (Rhizen Pharmaceuticals; 15.05.2018; IN-prior. 27.05.2014).
    • US 99 999 999 (Rhizen Pharmaceuticals; 11.09.2018; IN-prior. 04.07.2012; USA-prior. 21.08.2012).
    • US 99 999 999 (Rhizen Pharmaceuticals; 17.09.2019; IN-prior. 27.05.2014).
    • US 99 999 999 (Rhizen Pharmaceuticals; 25.02.2020; IN-prior. 04.07.2012; USA-prior. 21.08.2012).
    • US 99 999 999 (Rhizen Pharmaceuticals; 16.03.2021; IN-prior. 27.05.2014).
    • WO 9999 999999 (Incozen Therapeutics, Rhizen Pharmaceuticals; publ. 12.05.2011; IN-prior. 05.11.2009, 24.05.2010; USA-prior. 15.07.2010).
    • WO 9999 999999 (Rhizen Pharmaceuticals; publ. 09.01.2014; IN-prior. 04.07.2012; USA-prior. 21.08.2012).
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