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Zileuton

  • Synonyms: A-64077, ABT-077
  • Use: Lorem  Lorem  Lorem 
  • Chemical name: Lorem ipsum dolor sit amet, consetetur sadipscing elitr, sed diam
  • Formula: Lorem ipsum dolor sit amet,
  • MW:236.30 g/mol
  • CAS-RN:111406-87-2
  • InChI Key:MWLSOWXNZPKENC-UHFFFAOYSA-N
  • InChI:InChI=1S/C11H12N2O2S/c1-​7(13(15)​11(12)​14)​10-​6-​8-​4-​2-​3-​5-​9(8)​16-​10/h2-​7,​15H,​1H3,​(H2,​12,​14)

Substance Classes

Synthesis Path

















Substances Referenced in Synthesis Path

CAS-RN Formula Chemical Name CAS Index Name
75-07-0 C2H4O acetaldehyde Acetaldehyde
22720-75-8 C10H8OS 2-acetylbenzo[b]thiophene Ethanone, 1-benzo[b]thien-2-yl-
118564-89-9 C10H11NOS N-[1-(benzo[b]thien-2-yl)ethyl]hydroxylamine Benzo[b]thiophene-2-methanamine, N-hydroxy-α-methyl-
95-15-8 C8H6S benzo[b]thiophene Benzo[b]thiophene
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem

Trade Names

Country Trade Name Vendor Annotation
USA Lorem Lorem
(wfm = withdrawn from market)

Formulations

  • Loremipsumdolor

References

    • a US 9 999 999 (Abbott; 10.10.1989; appl. 11.1.1988; USA-prior. 10.2.1987, 10.6.1987).
    •  EP 999 999 (Abbott Lab.; appl. 1.2.1988; USA-prior. 10.2.1987).
    •  EP 999 999 (Abbott Lab.; appl. 6.9.1990; USA-prior. 7.9.1989).
    •  Brooks, C.D. W. et al.: J. Med. Chem. (JMCMAR) 38, 9999 (1995).
    • b EP 999 999 (Elf Sanofi; appl. 21.9.1993; F-prior. 22.9.1992).
    • c Stewart, A.O.; Brooks, D.W.: J. Org. Chem. (JOCEAH) 57, 9999 (1992).
  • alternative synthesis:

    • Ku, Y.-Y. et al.: Tetrahedron Lett. (TELEAY) 35 (33), 9999 (1994).
  • preparation of trimethylsilylisocyanate:

    • Kijima, J. at al.: Nippon Kagaku Kaishi (NKAKB8) 7, 1157-60 (1989),
    • EP 99 999 (Bayer AG; appl. 25.5.1982; D-prior. 3.6.1981).
  • use as anticancer agent:

    • WO 9 999 999 (US Dept. Health; appl. 14.3.1995; USA-prior. 14.3.1994).
  • use for treatment of neurodegenerative diseases:

    • WO 9 999 999 (Università Brescia; appl. 13.11.1997; I-prior. 13.11.1996).
  • combinations with COX-2-inhibitors:

    • WO 9 999 999 (G. D. Searle and Co.; appl. 11.6.1996; USA-prior. 12.6.1995).
    • WO 9 999 999 (G. D. Searle and Co.; appl. 12.2.1997; USA-prior. 13.2.1996).
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