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Agomelatine

  • Synonyms: S-20098, AG 0178
  • ATC: N06AX22
  • Use: Lorem  Lorem 
  • Chemical name: Lorem ipsum dolor sit amet, consetetur sadipscing elitr, sed diam
  • Formula: Lorem ipsum dolor sit amet,
  • MW:243.31 g/mol
  • CAS-RN:138112-76-2
  • InChI Key:YJYPHIXNFHFHND-UHFFFAOYSA-N
  • InChI:InChI=1S/C15H17NO2/c1-​11(17)​16-​9-​8-​13-​5-​3-​4-​12-​6-​7-​14(18-​2)​10-​15(12)​13/h3-​7,​10H,​8-​9H2,​1-​2H3,​(H,​16,​17)

Substance Classes

Synthesis Path












Substances Referenced in Synthesis Path

CAS-RN Formula Chemical Name CAS Index Name
75-36-5 C2H3ClO acetyl chloride Acetyl chloride
999-55-3 C6H8O2 allyl acrylate -
372-09-8 C3H3NO2 cyanoacetic acid Acetic acid, cyano-
105-36-2 C4H7BrO2 ethyl bromoacetate Acetic acid, bromo-, ethyl ester
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem

Trade Names

Country Trade Name Vendor Annotation
D Lorem Lorem ,2009
F Lorem Lorem ,2009
GB Lorem Lorem ,2009
I Lorem Lorem ,2009
(wfm = withdrawn from market)

Formulations

  • Loremipsumdolorsit

References

    • a Leclerc, V. et al.: Bioorg. Med. Chem. (BMECEP) 6, 10, 1875-1887 (1998).
    •  EP 9 999 999 (ADIR & Co.; 18.9.1991; appl. 27.2.1991; F-prior. 27.2.1990).
    • b EP 9 999 999 (LES Labo. Servier; 17.8.2005; appl. 11.2.2005; F-prior. 13.2.2004).
    •  US 9 999 999 (LES Labo. Servier; 13.1.2009; appl. 7.2.2005; F-prior. 13.2.2004).
  • crystalline form V of agomelatine:

    • US 9 999 999 (Servier Lab.; 30.11.2006; appl. 2.8.2006; F-prior. 3.8.2005).
  • crystalline form IV of agomelatine:

    • US 99 999 999 999 (LES Labo. Servier; 30.11.2006; appl. 2.8.2006; F-prior. 8.3.2005).
  • new crystalline form III of agomelatine:

    • EP 9 999 999 (Servier Lab.; 31.12.2008; appl. 2.8.2006; F-prior. 3.8.2005).
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