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Avapritinib

  • Synonyms: BLU-285
  • ATC: L01XE
  • Use: Lorem 
  • Chemical name: Lorem ipsum dolor sit amet, consetetur sadipscing elitr, sed diam
  • Formula: Lorem ipsum dolor sit amet,
  • MW:498.56 g/mol
  • CAS-RN:1703793-34-3
  • InChI Key:DWYRIWUZIJHQKQ-SANMLTNESA-N
  • InChI:InChI=1S/C26H27FN10/c1-26(28,20-3-5-22(27)6-4-20)21-13-29-25(30-14-21)36-9-7-35(8-10-36)24-23-11-18(16-37(23)33-17-31-24)19-12-32-34(2)15-19/h3-6,11-17H,7-10,28H2,1-2H3/t26-/m0/s1

Substance Classes

Synthesis Path




Substances Referenced in Synthesis Path

CAS-RN Formula Chemical Name CAS Index Name
1703797-335 C10H8ClN5 4-chloro-(6-(1-methyl)-1H-pyrazol-4-yl)-pyrrolo[2,1-f][1,2,4]triazine
C25H22FN9O (4-fluorophenyl)-(2-(4-(6-(1-methyl-1H-pyrazol-4-yl)pyrrolo[2,1-f][1,2,4]triazin-4-yl)-piperazin-1-yl)pyrimidin-5-yl)methanone
C4H11NOS (S)-2-methylpropane-2-sulfinamide

Trade Names

Country Trade Name Vendor Annotation
USA Lorem Lorem
(wfm = withdrawn from market)

Formulations

  • Loremipsumdolorsitamet,consetetursadipscing

References

    • Wu, C.-P. et al., Mol. Pharmaceutics, (2019) 16(7), 3040-3052.
    • US 9 999 999 (Blueprint Medicines; 12.6.2018; appl. 20.10.2015; USA-prior. 17.10.2013).