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Entrectinib

  • Synonyms: RXDX-101; NMS-E628
  • ATC: L01XE56
  • Use: Lorem 
  • Chemical name: Lorem ipsum dolor sit amet, consetetur sadipscing elitr, sed diam
  • Formula: Lorem ipsum dolor sit amet,
  • MW:560.7 g/mol
  • CAS-RN:1108743-60-7

Substance Classes

Synthesis Path




Substances Referenced in Synthesis Path

CAS-RN Formula Chemical Name CAS Index Name
C7H5BFNO2 3-cyano-4-fluoro-phenyl-boronic acid
C7H5BrF2 3,5-difluoro-benzylbromide
C14H11F2N3 5-(3,5-difluorobenzyl)-1H-imidazol-3-ylamine
C19H24F3N3O4 4-(4-methyl-piperazin-1-yl)-2-[(tetrahydro-pyran-4-yl)-(2,2,2-trifluoro-acetyl)-amino benzoic acid trifluoroacetate

Trade Names

Country Trade Name Vendor Annotation
USA Lorem Lorem
J Lorem Lorem
(wfm = withdrawn from market)

Formulations

  • Loremipsumdolorsitamet,consetetur

References

    • a) Menichincheri, M., J. Med. Chem., (2016) 59, 3392-3408.
    • US 9 999 999 (Nerviano Medical Sciences; 30.10.2012; appl. 8.7.2008; EP-prior. 20.7.2007).
    • US 9 999 999 (Nerviano Medical Sciences; 19.2.2015; appl. 30.10.2014; EP-prior. 23.5.2012).
  • Pharmaceutical compositions and dosage forms:

    • US 9999 999999 (Ignyta Inc.; 24.1.2019; appl. 18.7.2018; USA-prior. 19.7.2017).