Please log in to see the full text of this API!
Entrectinib
-
Synonyms:
RXDX-101; NMS-E628
-
ATC:
L01EX14
-
Use:
Lorem
-
Chemical name:
Lorem ipsum dolor sit amet, consetetur sadipscing elitr, sed diam
-
Formula:
Lorem ipsum dolor sit amet,
-
MW:560.7 g/mol
-
CAS-RN:1108743-60-7
-
InChI Key:HAYYBYPASCDWEQ-UHFFFAOYSA-N
-
InChI:InChI=1S/C31H34F2N6O2/c1-38-8-10-39(11-9-38)25-3-4-26(29(19-25)34-24-6-12-41-13-7-24)31(40)35-30-27-17-20(2-5-28(27)36-37-30)14-21-15-22(32)18-23(33)16-21/h2-5,15-19,24,34H,6-14H2,1H3,(H2,35,36,37,40)
Synthesis Path
Substances Referenced in Synthesis Path
| CAS-RN |
Formula |
Chemical Name |
CAS Index Name |
| 214210-21-6 |
C7H5BFNO2 |
3-cyano-4-fluoro-phenyl-boronic acid |
|
| 141776-91-2 |
C7H5BrF2 |
3,5-difluoro-benzylbromide |
|
| 1108745-30-7 |
C14H11F2N3 |
5-(3,5-difluorobenzyl)-1H-imidazol-3-ylamine |
|
|
C19H24F3N3O4 |
4-(4-methyl-piperazin-1-yl)-2-[(tetrahydro-pyran-4-yl)-(2,2,2-trifluoro-acetyl)-amino benzoic acid trifluoroacetate |
|
Trade Names
| Country |
Trade Name |
Vendor |
Annotation |
| USA |
Lorem |
Lorem
|
|
| J |
Lorem |
Lorem
|
|
| EU |
Lorem |
Lorem
|
|
(wfm = withdrawn from market)
Formulations
- Loremipsumdolorsitamet,consetetur
References
-
- a) Menichincheri, M., J. Med. Chem., (2016) 59, 3392-3408.
- US 9 999 999 (Nerviano Medical Sciences; 30.10.2012; appl. 8.7.2008; EP-prior. 20.7.2007).
- US 9 999 999 (Nerviano Medical Sciences; 19.2.2015; appl. 30.10.2014; EP-prior. 23.5.2012).
-
Pharmaceutical compositions and dosage forms:
- US 9999 999999 (Ignyta Inc.; 24.1.2019; appl. 18.7.2018; USA-prior. 19.7.2017).
