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Fedratinib
  • Synonyms: SAR-302503; UH9J2HBQWJ; TG-101348 (free base)
  • ATC: L01EJ02
  • Use: Lorem 
  • Chemical name: Lorem ipsum dolor sit amet, consetetur sadipscing elitr, sed diam
  • Formula: Lorem ipsum dolor sit amet,
  • MW:524.68 g/mol
  • CAS-RN:936091-26-8
  • InChI Key:JOOXLOJCABQBSG-UHFFFAOYSA-N
  • InChI:InChI=1S/C27H36N6O3S/c1-​20-​19-​28-​26(30-​21-​10-​12-​23(13-​11-​21)​36-​17-​16-​33-​14-​5-​6-​15-​33)​31-​25(20)​29-​22-​8-​7-​9-​24(18-​22)​37(34,​35)​32-​27(2,​3)​4/h7-​13,​18-​19,​32H,​5-​6,​14-​17H2,​1-​4H3,​(H2,​28,​29,​30,​31)

Derivatives

    Dihydrochloride hydrate

  • Formula: C27H40Cl2N6O4S
  • MW:615.62 g/mol
  • CAS-RN:1374744-69-0

Substance Classes

Synthesis Path



Substances Referenced in Synthesis Path

CAS-RN Formula Chemical Name CAS Index Name
308283-47-8 C10H14BrNO2S 3-bromo-N-tert. butylbenzyl-sulfonamide
155-10-2 C5H6ClN3 4-Amino-2-chloro-5-methyl-pyrimidine
50609-01-3 C12H18N2O 4-[2-pyrrolidin-1-yl-ethoxy]phenylamine
75-64-9 C4H11N tert. butylamine
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem

Trade Names

Country Trade Name Vendor Annotation
USA Lorem Lorem
(wfm = withdrawn from market)

Formulations

  • Loremipsumdolorsitamet,consetetur

References

    • WO 9999 999999 (TargeGen; 10.05.2007; USA-prior. 01.11.2005).
    • EP 9 999 999 (TargeGen; 26.10.2006; USA-prior. 01.11.2005).
    • US 9 999 999 (TargeGen; 05.05.2009; USA-prior. 01.11.2005).
    • US 9 999 999 (TargeGen; 02.10.2009; USA-prior. 01.11.2005).
    • WO 9999 999999 (TargeGen; 10.10.2009; USA-prior. 07.11.2010).

  • Preparation of II:

    • Odingo, Joshua et al., Bioorganic & Medicinal Chemistry, (2014) 22(24), 6965-6979.
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