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Voxelotor
  • Synonyms: GBI 440; GTX-011
  • ATC: -
  • Use: Lorem 
  • Chemical name: Lorem ipsum dolor sit amet, consetetur sadipscing elitr, sed diam
  • Formula: Lorem ipsum dolor sit amet,
  • MW:337.38 g/mol
  • CAS-RN:1446321-46-5
  • InChI Key:FWCVZAQENIZVMY-UHFFFAOYSA-N
  • InChI:InChI=1S/C19H19N3O3/c1-​13(2)​22-​16(8-​10-​21-​22)​19-​14(5-​4-​9-​20-​19)​12-​25-​18-​7-​3-​6-​17(24)​15(18)​11-​23/h3-​11,​13,​24H,​12H2,​1-​2H3

Substance Classes

Synthesis Path






Substances Referenced in Synthesis Path

CAS-RN Formula Chemical Name CAS Index Name
C12H15N3O 2-((1-isopropyl-1H-pyrazol-5-yl)-pyridin-3-yl)methanol
C12H14ClN3 3-(chloromethyl)-2-(1-isopropyl-1H-pyrazol-5-yl)-pyridine
387-46-2 C7H6O3 2,6-dihydroxy-benzaldehyde
6751-75-3 C6H5BrO2 2-bromo-benzene-1,3-diol

Trade Names

Country Trade Name Vendor Annotation
USA Lorem Lorem
(wfm = withdrawn from market)

Formulations

  • Loremipsumdolorsit

References

    • Vichinsky, E. et al, NEJM, (2019) 381(6), 509-519.
    • a) Metcalf, B. et al., ACS Med. Chem. Lett., (2017) 8(3), 321-326.
    • b) US 9 999 999 (Global Blood Therapeutics; 18.8.2015; appl. 6.2.2015; USA-prior. 7.2.2014).
    • US 9999 999999 (Global Blood Therapeutics; 21.7.2016; appl. 25.8.2014; USA-prior. 27.8.2013).
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