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Acarbose
  • Synonyms: Bay-g-5421
  • ATC: A10BF01
  • Use: Lorem  Lorem  Lorem 
  • Chemical name: Lorem ipsum dolor sit amet, consetetur sadipscing elitr, sed diam
  • Formula: Lorem ipsum dolor sit amet,
  • MW:645.61 g/mol
  • CAS-RN:56180-94-0
  • InChI Key:XUFXOAAUWZOOIT-SXARVLRPSA-N
  • InChI:InChI=1S/C25H43NO18/c1-​6-​11(26-​8-​2-​7(3-​27)​12(30)​15(33)​13(8)​31)​14(32)​19(37)​24(40-​6)​43-​22-​10(5-​29)​42-​25(20(38)​17(22)​35)​44-​21-​9(4-​28)​41-​23(39)​18(36)​16(21)​34/h2,​6,​8-​39H,​3-​5H2,​1H3/t6-,​8+,​9-,​10-,​11-,​12-,​13+,​14+,​15+,​16-,​17-,​18-,​19-,​20-,​21-,​22-,​23-,​24-,​25-​/m1/s1
  • EINECS:260-030-7
  • LD50: >500.000 SIE/kg (M, i.v.); >1.000.000 SIE/kg (M, p.o.);
    478.000 SIE/kg (R, i.v.); >1.000.000 SIE/kg (R, p.o.)
    65.000 SIE = 1g (SIE = saccharase inhibitory units)

Substance Classes

Enzymes

Synthesis Path
  • Fermentation of Actinoplanes SE50/110.

Trade Names

Country Trade Name Vendor Annotation
D Lorem Lorem ,1990
F Lorem Lorem
GB Lorem Lorem
I Lorem Lorem
J Lorem Lorem
USA Lorem Lorem
(wfm = withdrawn from market)

Formulations

  • Loremipsumdolorsitamet,

References

    • US 9 999 999 (Bayer; 13.12.1977; D-prior. 22.9.1973).
    • DOS 9 999 999 (Bayer; appl. 21.9.1973).
    • Schmidt, D.D. et al.: Naturwissenschaften (NATWAY) 64, 999 (1977).

  • purification process:

    • US 9 999 999 (Bayer; 27.2.1990; D-prior. 13.12.1985).

  • total synthesis:

    • Ogawa, S.; Shibata, Y.: Chem. Commun. (CCOMA8) 1988, 605.

  • review:

    • Tschesche, H.: in Arzneimittel, Fortschritte 1972-1985 (Ed. A. Kleemann, E. Lindner, J. Engel), p. 87, VCH Verlagsgesellschaft, Weinheim 1987.
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