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Acarbose

  • Synonyms: Bay-g-5421
  • ATC: A10BF01
  • Use: Lorem  Lorem  Lorem 
  • Chemical name: Lorem ipsum dolor sit amet, consetetur sadipscing elitr, sed diam
  • Formula: Lorem ipsum dolor sit amet,
  • MW:645.61 g/mol
  • CAS-RN:56180-94-0
  • InChI Key:XUFXOAAUWZOOIT-SXARVLRPSA-N
  • InChI:InChI=1S/C25H43NO18/c1-6-11(26-8-2-7(3-27)12(30)15(33)13(8)31)14(32)19(37)24(40-6)43-22-10(5-29)42-25(20(38)17(22)35)44-21-9(4-28)41-23(39)18(36)16(21)34/h2,6,8-39H,3-5H2,1H3/t6-,8+,9-,10-,11-,12-,13+,14+,15+,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-/m1/s1
  • EINECS:260-030-7
  • LD50: >500.000 SIE/kg (M, i.v.); >1.000.000 SIE/kg (M, p.o.);
    478.000 SIE/kg (R, i.v.); >1.000.000 SIE/kg (R, p.o.)
    65.000 SIE = 1g (SIE = saccharase inhibitory units)

Substance Classes

Enzymes

Synthesis Path




  • Fermentation of Actinoplanes SE50/110.

Trade Names

Country Trade Name Vendor Annotation
D Lorem Lorem ,1990
F Lorem Lorem
GB Lorem Lorem
I Lorem Lorem
J Lorem Lorem
USA Lorem Lorem
(wfm = withdrawn from market)

Formulations

  • Loremipsumdolorsitamet,

References

    • Schmidt, D.D. et al.: Naturwissenschaften (NATWAY) 64, 535 (1977).
    • US 9 999 999 (Bayer; 13.12.1977; D-prior. 22.9.1973).
    • DOS 9 999 999 (Bayer; appl. 21.9.1973).
  • purification process:

    • US 9 999 999 (Bayer; 27.2.1990; D-prior. 13.12.1985).
  • total synthesis:

    • Ogawa, S.; Shibata, Y.: Chem. Commun. (CCOMA8) 1988, 605.
  • review:

    • Tschesche, H.: in Arzneimittel, Fortschritte 1972-1985 (Ed. A. Kleemann, E. Lindner, J. Engel), p. 87, VCH Verlagsgesellschaft, Weinheim 1987.