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Acemetacin
  • ATC: M01AB11
  • Use: Lorem  Lorem  Lorem 
  • Chemical name: Lorem ipsum dolor sit amet, consetetur sadipscing elitr, sed diam
  • Formula: Lorem ipsum dolor sit amet,
  • MW:415.83 g/mol
  • CAS-RN:53164-05-9
  • InChI Key:FSQKKOOTNAMONP-UHFFFAOYSA-N
  • InChI:InChI=1S/C21H18ClNO6/c1-​12-​16(10-​20(26)​29-​11-​19(24)​25)​17-​9-​15(28-​2)​7-​8-​18(17)​23(12)​21(27)​13-​3-​5-​14(22)​6-​4-​13/h3-​9H,​10-​11H2,​1-​2H3,​(H,​24,​25)
  • EINECS:258-403-4
  • LD50:55 mg/kg (Mm, p.o.); 18.42mg/kg (Mf, p.o.);
    24.2 mg/kg (Rm, p.o.); 30.1 mg/kg (Rf, p.o.)

Substance Classes

Synthesis Path











Substances Referenced in Synthesis Path

CAS-RN Formula Chemical Name CAS Index Name
104-94-9 C7H9NO p-anisidine Benzenamine, 4-methoxy-
5437-45-6 C9H9BrO2 benzyl bromoacetate Acetic acid, bromo-, phenylmethyl ester
140-18-1 C9H9ClO2 benzyl chloroacetate
53164-04-8 C28H24ClNO6 benzyl [1-(4-chlorobenzoyl)-5-methoxy-2-methyl-3-indolylacetoxy]acetate 1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-, 2-oxo-2-(phenylmethoxy)ethyl ester
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem

Trade Names

Country Trade Name Vendor Annotation
D Lorem Lorem
Lorem Lorem
GB Lorem Lorem
I Lorem Lorem
Lorem Lorem wfm
J Lorem Lorem
(wfm = withdrawn from market)

Formulations

  • Loremipsumdolorsitamet,consetetursadipscingelitr,seddiamnonumyeirmodtempor

References

    • DE 9 999 999 (Tropon; appl. 14.7.1972).
    • FR 9 999 999 (Tropon; appl. 13.7.1973; D-prior. 14.7.1972).
    • US 9 999 999 (Troponwerke Dinklage; 7.10.1975; appl. 28.6.1973; D-prior. 14.7.1972).

  • preparation of 4-methoxyphenylhydrazine from 4-methoxyaniline (p-anisidine):

    • Lee, A.-R. et al.: J. Heterocycl. Chem. (JHTCAD) 32 (1), 1-12 (1995).
    • Clade, D.W. et al.: J. Chem. Soc., Perkin Trans. 9 (JCPKBH) , 909-916 (1982).
    • DE 99 999 (Riedel; 12.11.1891).
    • Altschul: Ber. Dtsch. Chem. Ges. (BDCGAS) 25, 9999 (1892).

  • preparation of benzyl levulinoyloxyacetate:

    • Boltze, K.-H.; Brendler, O.; Jacobi, H.; Opitz, W.; Raddatz, S. et al.: Arzneim.-Forsch. (ARZNAD) 30 (8a), 1314-1325 (1980).
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