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5-Aminolevulinic acid

  • Synonyms: ALA, δ-Aminolevulinic acid
  • ATC: L01XD04
  • Use: Lorem  Lorem 
  • Chemical name: Lorem ipsum dolor sit amet, consetetur sadipscing elitr, sed diam
  • Formula: Lorem ipsum dolor sit amet,
  • MW:131.13 g/mol
  • CAS-RN:106-60-5
  • InChI Key:ZGXJTSGNIOSYLO-UHFFFAOYSA-N
  • InChI:InChI=1S/C5H9NO3/c6-​3-​4(7)​1-​2-​5(8)​9/h1-​3,​6H2,​(H,​8,​9)

Derivatives

    hydrochloride

  • Use:
  • Formula: Lorem ipsum dolor sit amet,
  • MW:167.59 g/mol
  • CAS-RN:5451-09-2

    methyl ester hydrochloride

  • Use:
  • Formula: Lorem ipsum dolor sit amet,
  • MW:181.62 g/mol
  • CAS-RN:79416-27-6

Substance Classes

Synthesis Path








Substances Referenced in Synthesis Path

CAS-RN Formula Chemical Name CAS Index Name
495-69-2 C9H9NO3 hippuric acid -
5154-01-8 C5H5NO2 5-hydroxy-2-pyridone -
29491-94-9 C14H13NO5 methyl 4-oxo-4-(5-oxo-2-phenyl-4H-1,3-oxazol-4-yl)butanoate 2-phenyl-4-(β-carbomethoxypropionyl)-5-oxazolinone-
1490-25-1 C5H7ClO3 methyl 4-chloro-4-oxobutanoate Methyl succinyl chloride
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem

Trade Names

Country Trade Name Vendor Annotation
D Lorem Lorem
GB Lorem Lorem
Lorem Lorem
I Lorem Lorem
USA Lorem ipsum Lorem
USA Lorem Lorem
EU Lorem Lorem
USA Lorem Lorem
EU Lorem Lorem
(wfm = withdrawn from market)

Formulations

  • Loremipsumdolorsitamet,consetetursadipscingelitr,seddiamnonumyeirmodtemporinviduntutlaboreet

References

    • a Herdeis, C.; Dimmerling, A., Arch. Pharm. (Weinheim, Ger.), (1984) 317, 304.
    • b US 9 999 999 (Aronova, N.I. et al.; 5.11.1974; appl. 1.3.1972).
    • c MacDonald, S. F., Can. J. Chem., (1974) 52, 3257.
    • Benedikt, E.; Köst, H.-P., Z. Naturforschung, (1986) 41, 1593.
    • Zai, Y. et al., RSC Adv., (2019) 9, 10091.
    • US 9 999 999 B1 (L. Moens, Midwest Research Institute); 24.6.2003; appl. 18.10.2000; USA-prior. 18.10.2000).
  • Alternative synthesis:

    • Battersby, A. R. et al., J. Chem. Soc., Perkin Trans. 1, (1973), 2917.
    • Evans, A.; Sidebottom, P.-J., J. Chem. Soc., Chem. Commun., (1973), 753.
    • Wynn, R.; Corwyn, A., J. Org. Chem., (1950) 15, 203.
  • Preparation from furfurylamine:

    • US 9 999 999 (Cosmo Res. Inst.; 10.1.1995; J-prior. 20.1.1993, 3.12.1993).
  • Review:

    • L. Moens, ACS Symp. Ser., (2001) 784, 37.
  • Methods for pharmacodynamic therapy:

    • US 99 999 999 B1 (Dusa Pharmaceuticals; 23.7.2019; appl. 12.1.2018; USA-prior. 12.1.2018).
    • US 99 999 999 (Dusa Pharmaceuticals; 4.7.2023; appl. 28.7.2022; USA-prior. 12.1.2018).
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