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Abrocitinib
-
Synonyms:
PF-04965842
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ATC:
D11AH08
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Use:
Lorem
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Chemical name:
Lorem ipsum dolor sit amet, consetetur sadipscing elitr, sed diam
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Formula:
Lorem ipsum dolor sit amet,
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MW:323.41 g/mol
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CAS-RN:1622902-68-4
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InChI Key:IUEWXNHSKRWHDY-PHIMTYICSA-N
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InChI:InChI=1S/C14H21N5O2S/c1-3-6-22(20,21)18-10-7-11(8-10)19(2)14-12-4-5-15-13(12)16-9-17-14/h4-5,9-11,18H,3,6-8H2,1-2H3,(H,15,16,17)/t10-,11+
Synthesis Path
Substances Referenced in Synthesis Path
| CAS-RN |
Formula |
Chemical Name |
CAS Index Name |
| 23761-23-1 |
C5H6O3 |
3-oxocyclobutane-1-carboxylic acid |
|
| 130369-36-7 |
C12H13NO3 |
benzyl 3-oxocyclobutyl-carbamate |
|
| 2204290-99-1 |
C13H19ClN2O2 |
benzyl [cis(methylamino)-cyclobutyl]carbamate hydrochloride |
|
|
C13H10ClN3O2S |
N-tosyl-6-chloro-7-deazapurine |
|
| Lorem |
Lorem |
Lorem |
Lorem |
| Lorem |
Lorem |
Lorem |
Lorem |
| Lorem |
Lorem |
Lorem |
Lorem |
| Lorem |
Lorem |
Lorem |
Lorem |
| Lorem |
Lorem |
Lorem |
Lorem |
| Lorem |
Lorem |
Lorem |
Lorem |
| Lorem |
Lorem |
Lorem |
Lorem |
Trade Names
| Country |
Trade Name |
Vendor |
Annotation |
| J |
Lorem |
Lorem
|
|
| GB |
Lorem |
Lorem
|
|
| EU |
Lorem |
Lorem
|
|
| USA |
Lorem |
Lorem
|
|
(wfm = withdrawn from market)
Formulations
- Loremipsumdolorsitamet,consetetursadipscing
References
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- Bieber, T. et al., N. Engl. J. Med., (2021) 384, 1101-1112.
- a) Vazquez, M.L. et al., J. Med. Chem., (2018) 61(3), 1130-1152.
- US 9 999 999 (Pfizer; 19.5.2015; appl. 19.2.2014; USA-prior. 22.2.2013).
- US 9 999 999 (Pfizer; 24.1.2017; appl. 18.5.2015; USA-prior. 22.2.2013).
- b) Connor, C.G. et al., Org. Process Res. Dev., (2021) 25, 608-615.
- WO 9999 999999 (Pfizer; 9.1.2020; appl. 3.7.2019; USA-prior. 6.7.2018).
- US 99 999 999 (Pfizer; 22.2.2022; appl. 29.9.2020; USA-prior. 6.7.2018).
- Kocienski, P., Synfacts, (2021) 17(6), 0606.
- a+b) Zhan, D.G. et al., Drugs of the Future, (2021) 46(6), 431-441.
