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Ademetionine
  • Synonyms: Adenosylmethionine, Methioninyl adenylate, SAM
  • ATC: A16AA02
  • Use: Lorem 
  • Chemical name: Lorem ipsum dolor sit amet, consetetur sadipscing elitr, sed diam
  • Formula: Lorem ipsum dolor sit amet,
  • MW:398.44 g/mol
  • CAS-RN:29908-03-0
  • InChI Key:MEFKEPWMEQBLKI-AIRLBKTGSA-N
  • InChI:InChI=1S/C15H22N6O5S/c1-​27(3-​2-​7(16)​15(24)​25)​4-​8-​10(22)​11(23)​14(26-​8)​21-​6-​20-​9-​12(17)​18-​5-​19-​13(9)​21/h5-​8,​10-​11,​14,​22-​23H,​2-​4,​16H2,​1H3,​(H2-,​17,​18,​19,​24,​25)/t7-,​8+,​10+,​11+,​14+,​27?/m0/s1
  • EINECS:249-946-8

Substance Classes

Enzymes

Synthesis Path
  • Preparation by fermentation of Saccharomyces cerevisiae (baker yeast) with addition of l- or dl-methionine, lyse of cells with ethyl acetate and purification by ion-exchange chromatography.

Trade Names

Country Trade Name Vendor Annotation
D Lorem Lorem
I Lorem Lorem
Lorem Lorem
Lorem Lorem
(wfm = withdrawn from market)

Formulations

  • Loremipsumdolorsitamet,consetetursadipscingelitr,seddiam

References

  • fermentation and isolation:

    • Schlenk: Enzymologia (ENZYAS) 29, 999 (1965).
    • DE 9 999 999 (Boehringer Mannh.; appl. 18.10.1968).
    • US 9 999 999 (Ajinomoto; 8.6.1976; J-prior. 27.11.1973).
    • DOS 9 999 999 (Nippon Zeon; appl. 25.8.1982).
    • DOS 9 999 999 (Nippon Zeon; appl. 9.2.1983; J-prior. 25.2.1982, 26.2.1982).
    • DOS 9 999 999 (Nippon Zeon; appl. 12.8.1983; J-prior. 13.8.1982).

  • stable salts:

  • 4-toluenesulfonates:

    • DOS 9 999 999 (Errekappa Euroterapici; appl. 17.7.1973; I-prior. 2.8.1972).
    • US 9 999 999 (Bioresearch; 8.7.1975; I-prior. 2.8.1972).

  • 4-toluenesulfonate sulfates:

    • US 9 999 999 (Bioresearch; 4.5.1976; I-prior. 27.6.1973; 24.5.1974).

  • other sulfonates:

    • DOS 9 999 999 (Bioresearch; appl. 10.7.1975; I-prior. 12.7.1974).
    • US 9 999 999 (Bioresearch; 8.11.1977; I-prior. 12.7.1974).
    • US 9 999 999 (Bioresearch; 14.8.1984; I-prior. 24.8.1981).
    • EP 99 999 (Bioresearch; appl. 12.8.1982; I-prior. 24.8.1981).
    • EP 999 999 (Bioresearch; appl. 25.4.1985; I-prior. 16.5.1984).
    • EP 999 999 (Bioresearch; appl. 25.4.1985; I-prior. 16.5.1984).

  • other salts:

    • EP 99 999 (Bioresearch; appl. 12.8.1982; I-prior. 24.8.1981).
    • EP 99 999 (Bioresearch; appl. 30.8.1982; I-prior. 11.9.1981).
    • EP 999 999 (Kanegafuchi; appl. 6.11.1982).
    • EP 999 999 (Tecofar; appl. 19.10.1984; I-prior. 26.10.1983).

  • formulations:

  • injection form:

    • EP 999 999 (Bioresearch; appl. 1.8.1984; I-prior. 24.8.1983).

  • gastric juice resistant form:

    • EP 999 999 (Bioresearch; appl. 1.8.1984; I-prior. 24.8.1983).
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