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Afamelanotide
- Synonyms: Melanotan; NDP-MSH; EPT1647; CUV1647
- ATC: D02BB02
- Use: Lorem
- Chemical name: Lorem ipsum dolor sit amet, consetetur sadipscing elitr, sed diam
- Formula: Lorem ipsum dolor sit amet,
- MW:1646.8 g/mol
- CAS-RN:75921-69-6
- InChI Key:UAHFGYDRQSXQEB-LEBBXHLNSA-N
- InChI:InChI=1S/C78H111N21O19/c1-5-6-19-52(91-75(116)61(41-101)97-72(113)57(34-46-24-26-49(103)27-25-46)94-74(115)60(40-100)88-44(4)102)68(109)92-54(28-29-64(105)106)70(111)96-59(36-48-38-83-42-87-48)73(114)93-56(33-45-16-8-7-9-17-45)71(112)90-53(22-14-31-84-78(81)82)69(110)95-58(35-47-37-85-51-20-11-10-18-50(47)51)67(108)86-39-63(104)89-55(21-12-13-30-79)77(118)99-32-15-23-62(99)76(117)98-65(43(2)3)66(80)107/h7-11,16-18,20,24-27,37-38,42-43,52-62,65,85,100-101,103H,5-6,12-15,19,21-23,28-36,39-41,79H2,1-4H3,(H2,80,107)(H,83,87)(H,86,108)(H,88,102)(H,89,104)(H,90,112)(H,91,116)(H,92,109)(H,93,114)(H,94,115)(H,95,110)(H,96,111)(H,97,113)(H,98,117)(H,105,106)(H4,81,82,84)/t52-,53-,54-,55-,56+,57-,58-,59-,60-,61-,62-,65-/m0/s1
Substance Classes
Synthesis Path
- Afamelanotide is synthesized by solution phase peptide chemistry using commercially available starting materials.
Trade Names
Country | Trade Name | Vendor | Annotation |
---|---|---|---|
EU | Lorem | Lorem | |
USA | Lorem | Lorem |
Formulations
- Loremipsumdolorsitamet,consetetursadipscingelitr,seddiam
References
-
- Langendonk, J. G. et al., N. Engl. J. Med., (2015) 373, 48-59.
- US 9 999 999 (University of Arizona; 27.11.1984; appl. 11.6.1982).
-
α-MSH-derivatives for treatment of photodermatoses:
- EP 9 999 999 (Clinuvel; 29.4.2015; appl. 31.8.2007; AU-prior. 31.8.2006).