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Aldosterone

  • ATC: H02AA01
  • Use: Lorem 
  • Chemical name: Lorem ipsum dolor sit amet, consetetur sadipscing elitr, sed diam
  • Formula: Lorem ipsum dolor sit amet,
  • MW:360.45 g/mol
  • CAS-RN:52-39-1
  • InChI Key:PQSUYGKTWSAVDQ-ZVIOFETBSA-N
  • InChI:InChI=1S/C21H28O5/c1-​20-​7-​6-​13(24)​8-​12(20)​2-​3-​14-​15-​4-​5-​16(18(26)​10-​22)​21(15,​11-​23)​9-​17(25)​19(14)​20/h8,​11,​14-​17,​19,​22,​25H,​2-​7,​9-​10H2,​1H3/t14-,​15-,​16+,​17-,​19+,​20-,​21+/m0/s1
  • EINECS:200-139-9

Substance Classes

Synthesis Path








Substances Referenced in Synthesis Path

CAS-RN Formula Chemical Name CAS Index Name
297-91-6 C23H30O6 21-O-acetylaldosterone Pregn-4-en-18-al, 21-(acetyloxy)-11-hydroxy-3,20-dioxo-, (11β)-
74220-49-8 C23H31NO6 21-O-acetylaldosterone 18-oxime Pregn-4-en-18-al, 21-(acetyloxy)-11-hydroxy-3,20-dioxo-, 18-oxime, (11β)-
1173-26-8 C23H32O5 21-O-acetylcorticosterone Pregn-4-ene-3,20-dione, 21-(acetyloxy)-11-hydroxy-, (11β)-
74220-48-7 C23H31NO6 21-O-acetyl-11-O-nitrosylcorticosterone Pregn-4-ene-3,20-dione, 21-(acetyloxy)-11-(nitrosooxy)-, (11β)-
Lorem Lorem Lorem Lorem

Trade Names

Country Trade Name Vendor Annotation
D Lorem Lorem wfm
GB Lorem Lorem wfm
I Lorem ipsum Lorem comb. wfm
USA Lorem Lorem wfm
Lorem Lorem wfm
(wfm = withdrawn from market)

Formulations

  • Loremipsumdolorsitamet,

References

    • Barton, D.H.R.; Beaton, J.M.: J. Am. Chem. Soc. (JACSAT), 82, 9999 (1960).
  • starting material:

    • The Merck Index, 9999 (Rahway 1976).
  • alternative syntheses:

    • US 9 999 999 (Ciba; 3.10.1961; appl. 28.11.1958; CH-prior. 5.12.1957).
    • US 9 999 999 (Ciba; 19.12.1961; appl. 16.6.1959; CH-prior. 18.6.1958).
    • US 9 999 999 (Wisconsin Alumni Res. Found.; 14.8.1962; appl. 29.7.1957).
    • Wettstein, A. et al.: Helv. Chim. Acta (HCACAV) 44, 999 (1961).
    • Reichstein, T. et al.: Helv. Chim. Acta (HCACAV) 38, 9999 (1957).
  • review:

    • Fieser, L.F.; Fieser, M.: Steroide p. 999 ff, Verlag Chemie, Weinheim 1961.
  • total synthesis:

    • Johnson, P.S. et al.: J. Am. Chem. Soc. (JACSAT) 80, 9999 (1958).
    • Blickenstaff, R.T.; Ghosh, A.C.; Wolf, G.C.: Total Synthesis of Steroids (Organic Chemistry Vol. 30) p. 999 ff, Academic Press, New York, London 1974.
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