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Flurazepam
  • ATC: N05CD01
  • Use: Lorem  Lorem 
  • Chemical name: Lorem ipsum dolor sit amet, consetetur sadipscing elitr, sed diam
  • Formula: Lorem ipsum dolor sit amet,
  • MW:387.89 g/mol
  • CAS-RN:17617-23-1
  • InChI Key:SAADBVWGJQAEFS-UHFFFAOYSA-N
  • InChI:InChI=1S/C21H23ClFN3O/c1-​3-​25(4-​2)​11-​12-​26-​19-​10-​9-​15(22)​13-​17(19)​21(24-​14-​20(26)​27)​16-​7-​5-​6-​8-​18(16)​23/h5-​10,​13H,​3-​4,​11-​12,​14H2,​1-​2H3
  • EINECS:241-591-7
  • LD50:59.1 mg/kg (M, i.v.); 500 mg/kg (M, p.o.);
    38.7 mg/kg (R, i.v.); 980 mg/kg (R, p.o.)

Derivatives

    dihydrochloride

  • Use:
  • Formula: Lorem ipsum dolor sit amet,
  • MW:460.81 g/mol
  • CAS-RN:1172-18-5
  • EINECS:214-630-0
  • LD50:59.1 mg/kg (M, i.v.); 596 mg/kg (M, p.o.);
    38.7 mg/kg (R, i.v.); 879 mg/kg (R, p.o.)

    hydrochloride

  • Use:
  • Formula: Lorem ipsum dolor sit amet,
  • MW:424.35 g/mol
  • CAS-RN:36105-20-1

Substance Classes

Synthesis Path




Substances Referenced in Synthesis Path

CAS-RN Formula Chemical Name CAS Index Name
784-38-3 C13H9ClFNO 2-amino-5-chloro-2'-fluorobenzophenone Methanone, (2-amino-5-chlorophenyl)(2-fluorophenyl)-
32566-14-6 C21H27ClFN3O2 2-amino-N-[4-chloro-2-[(2-fluorophenyl)hydroxymethyl]phenyl]-N-[2-(diethylamino)ethyl]acetamide Acetamide, 2-amino-N-[4-chloro-2-[(2-fluorophenyl)hydroxymethyl]phenyl]-N-[2-(diethylamino)ethyl]-
22118-09-8 C2H2BrClO bromoacetyl chloride Acetyl chloride, bromo-
1584-62-9 C15H10BrClFNO2 2-bromo-N-[4-chloro-2-(2-fluorobenzoyl)phenyl]acetamide Acetamide, 2-bromo-N-[4-chloro-2-(2-fluorobenzoyl)phenyl]-
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem

Trade Names

Country Trade Name Vendor Annotation
D Lorem Lorem
Lorem ipsum Lorem
Lorem Lorem
I Lorem Lorem
Lorem Lorem
Lorem Lorem
Lorem Lorem
Lorem Lorem
J Lorem Lorem
USA Lorem Lorem
Lorem Lorem
(wfm = withdrawn from market)

Formulations

  • Loremipsumdolorsitamet,consetetursadipscingelitr,seddiamnonumyeirmodtemporinviduntutlaboreetdoloremagnaaliquyamerat,seddiamvoluptua.Atveroeosetaccusametjustoduo

References

    • US 9 999 999 (Hoffmann-La Roche; 2.3.1971; prior. 3.6.1968).
    • Inabra, S. et al.: Chem. Pharm. Bull. (CPBTAL) 19, 999 (1971).
    • Sternbach, L.H. et al.: J. Med. Chem. (JMCMAR) 8, 999 (1965).

  • alternative synthesis by reaction of 2-diethylaminoethyl chloride with 7-chloro-5-(2-fluorophenyl)-2-oxo-2,3-dihydro-1H-1,4-benzodiazepine:

    • GB 9 999 999 (Roche; appl. 1.3.1963; USA-prior. 2.3.1962).
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