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Fluticasone propionate
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ATC:
D07AC17; R01AD08; R03BA05
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Use:
Lorem
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Chemical name:
Lorem ipsum dolor sit amet, consetetur sadipscing elitr, sed diam
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Formula:
Lorem ipsum dolor sit amet,
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MW:500.58 g/mol
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CAS-RN:80474-14-2
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InChI Key:WMWTYOKRWGGJOA-CENSZEJFSA-N
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InChI:InChI=1S/C25H31F3O5S/c1-5-20(31)33-25(21(32)34-12-26)13(2)8-15-16-10-18(27)17-9-14(29)6-7-22(17,3)24(16,28)19(30)11-23(15,25)4/h6-7,9,13,15-16,18-19,30H,5,8,10-12H2,1-4H3/t13-,15+,16+,18+,19+,22+,23+,24+,25+/m1/s1
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LD50:>2 g/kg (R, p. o.); >1 g/kg (R, s. c.)
Substances Referenced in Synthesis Path
| CAS-RN |
Formula |
Chemical Name |
CAS Index Name |
| 74-97-5 |
CH2BrCl |
bromochloromethane |
Methane, bromochloro- |
| 28416-82-2 |
C21H26F2O5 |
(6α,11β,16α,17α)-6,9-difluoro-11,17-dihydroxy-16-methyl-3-oxoandrosta-1,4-diene-17-carboxylic acid |
Androsta-1,4-diene-17-carboxylic acid, 6,9-difluoro-11,17-dihydroxy-16-methyl-3-oxo-, (6α,11β,16α,17α)- |
| 80474-45-9 |
C24H30F2O5S |
(6α,11β,16α,17α)-6,9-difluoro-11-hydroxy-16-methyl-3-oxo-17-(1-oxopropoxy)androsta-1,4-diene-17-carbothioic acid |
Androsta-1,4-diene-17-carbothioic acid, 6,9-difluoro-11-hydroxy-16-methyl-3-oxo-17-(1-oxopropoxy)-, (6α,11β,16α,17α)- |
| 65429-42-7 |
C24H30F2O6 |
(6α,11β,16α,17α)-6,9-difluoro-11-hydroxy-16-methyl-3-oxo-17-(1-oxopropoxy)androsta-1,4-diene-17-carboxylic acid |
Androsta-1,4-diene-17-carboxylic acid, 6,9-difluoro-11-hydroxy-16-methyl-3-oxo-17-(1-oxopropoxy)-, (6α,11β,16α,17α)- |
| Lorem |
Lorem |
Lorem |
Lorem |
| Lorem |
Lorem |
Lorem |
Lorem |
| Lorem |
Lorem |
Lorem |
Lorem |
Trade Names
| Country |
Trade Name |
Vendor |
Annotation |
| D |
Lorem |
Lorem
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| Lorem |
Lorem
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| Lorem |
Lorem
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| Lorem |
Lorem
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| Lorem |
Lorem
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| Lorem |
Lorem
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comb. with salmeterol |
| F |
Lorem |
Lorem
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| Lorem |
Lorem
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| Lorem |
Lorem
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comb. |
| GB |
Lorem |
Lorem
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| Lorem |
Lorem
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| Lorem |
Lorem
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| I |
Lorem ipsum |
Lorem
Lorem
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comb. |
| Lorem |
Lorem
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| Lorem |
Lorem
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| Lorem |
Lorem
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| Lorem |
Lorem
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| Lorem ipsum |
Lorem
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comb. |
| J |
Lorem |
Lorem
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| Lorem |
Lorem
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| Lorem |
Lorem
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| USA |
Lorem |
Lorem
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| Lorem |
Lorem
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| Lorem |
Lorem
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| Lorem |
Lorem
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(wfm = withdrawn from market)
Formulations
- Loremipsumdolorsitamet,consetetursadipscingelitr,seddiamnonumyeirmodtemporinviduntutlaboreetdoloremagnaaliquyamerat,seddiamvoluptua.Atveroeos
References
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- DE 9 999 999 (Glaxo; appl. 13.2.1981; GB-prior. 15.2.1980).
- US 9 999 999 (Glaxo; 15.6.1982; appl. 13.2.1981; GB-prior. 15.2.1980).
- BE 999 999 (Glaxo Group; appl. 13.2.1981; GB-prior. 15.2.1980).
- IL 999 999 (Chemagis LTD.; IL-prior. 15.5.1994).
- Phillipps, G.H. et al.: J. Med. Chem. (JMCMAR) 37, 9999 (1994).
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17-carboxylic acid by periodic acid oxidation:
- US 9 999 999 (Glaxo; 6.6.1987; appl. 6.1.1977; GB-prior. 30.8.1974).
