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Fluvastatin sodium

  • Synonyms: SRI-62320, XU-62-320, XU-620
  • ATC: C10AA04
  • Use: Lorem  Lorem 
  • Chemical name: Lorem ipsum dolor sit amet, consetetur sadipscing elitr, sed diam
  • Formula: Lorem ipsum dolor sit amet,
  • MW:433.46 g/mol
  • CAS-RN:93957-55-2
  • InChI Key:ZGGHKIMDNBDHJB-NRFPMOEYSA-M
  • InChI:InChI=1S/C24H26FNO4.Na/c1-​15(2)​26-​21-​6-​4-​3-​5-​20(21)​24(16-​7-​9-​17(25)​10-​8-​16)​22(26)​12-​11-​18(27)​13-​19(28)​14-​23(29)​30;/h3-​12,​15,​18-​19,​27-​28H,​13-​14H2,​1-​2H3,​(H,​29,​30);/q;+1/p-​1/b12-​11+;/t18-,​19-​;/m1./s1

Derivatives

    free acid

  • Use:
  • Formula: Lorem ipsum dolor sit amet,
  • MW:411.47 g/mol
  • CAS-RN:93957-54-1

Substance Classes

Synthesis Path


























Substances Referenced in Synthesis Path

CAS-RN Formula Chemical Name CAS Index Name
1694-31-1 C8H14O3 tert-butyl acetoacetate Butanoic acid, 3-oxo-, 1,1-dimethylethyl ester
129332-29-2 C28H34FNO4 tert-butyl (±)-erythro-(E)-7-[3-(4-fluorophenyl)-1-isopropylindol-2-yl]-3,5-dihydroxyhept-6-enoate 6-Heptenoic acid, 7-[3-(4-fluorophenyl)-1-(1-methylethyl)-1H-indol-2-yl]-3,5-dihydroxy-, 1,1-dimethylethyl ester, [R*,S*-(E)]-(.+-.)-
- C28H32FNO4 tert-butyl (±)-(E)-7-[3-(4-fluorophenyl)-1-isopropylindol-2-yl]-5-hydroxy-3-oxohept-6-enoate -
456-04-2 C8H6ClFO α-chloro-p-fluoroacetophenone Ethanone, 2-chloro-1-(4-fluorophenyl)-
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem
Lorem Lorem Lorem Lorem

Trade Names

Country Trade Name Vendor Annotation
D Lorem Lorem
Lorem Lorem
F Lorem Lorem
Lorem Lorem
GB Lorem Lorem
I Lorem Lorem
Lorem Lorem
Lorem Lorem
J Lorem Lorem Lorem
USA Lorem Lorem
(wfm = withdrawn from market)

Formulations

  • Loremipsumdolorsitamet,consetetursadipscingelitr,seddiamnonumy

References

    • a US 9 999 999 (Sandoz; 11.10.1994; appl. 24.11.1993; USA-prior. 22.11.1982, 4.11.1983, 4.3.1985, 11.4.1985).
    •  WO 9 999 999 (Sandoz; appl. 18.11.1983; USA-prior. 22.11.1982, 4.11.1983, 4.3.1985).
    • aa Walkup, R.E. et al.: Tetrahedron Lett. (TELEAY) 26 (18), 2155-2158 (1985).
    • b EP 999 999 (Sandoz; appl. 11.10.1989; USA-prior. 13.10.1983, 22.5.1989).
  • review of synthetic processes:

    • Repiç,O. et al.: Org. Process Res. Dev. (OPRDFK) 5, 519-527 (2001).
  • composition with improved storage stability:

    • US 9 999 999 (Sandoz; 18.10.1994; appl. 22.12.1992; USA-prior. 12.12.1991).
  • oral pharmaceutical composition:

    • EP 999 999 (Sandoz; appl. 8.12.1992; USA-prior. 12.12.1991).
  • combination with squalene synthase inhibitors:

    • EP 999 999 (Squibb; appl. 16.10.1991; USA-prior. 19.10.1990).
    • EP 999 999 (Squibb; appl. 1.6.1990; USA-prior. 5.6.1989).
  • combination with ACE inhibitors:

    • EP 999 999 (Squibb; appl. 6.6.1991; USA-prior. 11.6.1990).
    • EP 999 999 (Squibb; appl. 10.5.1991; USA-prior. 15.5.1990).
  • combination with niacin or probucol:

    • EP 999 999 (Squibb; appl. 7.12.1982; USA-prior. 12.12.1988).
  • composition containing coenzyme Q10:

    • US 9 999 999 (Merck & Co.; 12.6.1990; appl. 18.1.1989; USA-prior. 18.1.1989).
    • US 9 999 999 (Merck & Co.; 29.5.1990; appl. 2.2.1989; USA-prior. 2.2.1989).
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